CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA

This investigation was aimed for studying efficacy of Betaleukin in combined therapy of influenza and flu-like respiratory diseases complicated by pneumonia, and development of inclusion criteria. Treatment with Betaleukin was significantly associated with shorter duration of catarrhal syndrome and...

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Autores principales:	L. V. Voloschchuk, E. G. Golovacheva, A. L. Mushkatina, L. V. Osidak, P. V. Zarishnyuk, A. A. Go
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	influenza pneumonia clinical pattern cytokines betaleukin therapeutic efficacy Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/c627294486594cb88eaa549352400c37
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spelling	oai:doaj.org-article:c627294486594cb88eaa549352400c372021-11-18T08:03:37ZCLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA1563-06252313-741X10.15789/1563-0625-2013-1-29-36https://doaj.org/article/c627294486594cb88eaa549352400c372014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/57https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThis investigation was aimed for studying efficacy of Betaleukin in combined therapy of influenza and flu-like respiratory diseases complicated by pneumonia, and development of inclusion criteria. Treatment with Betaleukin was significantly associated with shorter duration of catarrhal syndrome and decreased resolution terms of lung infiltrates. Usage of Betaleukin was shown to influence the levels of pro- and anti-inflammatory cytokines and interferons. Betaleukin is effective in patients under 50 years old, independent on initial volume of lung infiltrates. Full resolution of pneumonia treated with Betaleukin was observed in patients with initial IL-1β concentrations under 80 pg/ml, or 80-120 pg/ml, and IL-1rа concentrations of 500-1000 pg/ml in blood serum.L. V. VoloschchukE. G. GolovachevaA. L. MushkatinaL. V. OsidakP. V. ZarishnyukA. A. GoSPb RAACIarticleinfluenzapneumoniaclinical patterncytokinesbetaleukintherapeutic efficacyImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 1, Pp 29-36 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	influenza pneumonia clinical pattern cytokines betaleukin therapeutic efficacy Immunologic diseases. Allergy RC581-607
spellingShingle	influenza pneumonia clinical pattern cytokines betaleukin therapeutic efficacy Immunologic diseases. Allergy RC581-607 L. V. Voloschchuk E. G. Golovacheva A. L. Mushkatina L. V. Osidak P. V. Zarishnyuk A. A. Go CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA
description	This investigation was aimed for studying efficacy of Betaleukin in combined therapy of influenza and flu-like respiratory diseases complicated by pneumonia, and development of inclusion criteria. Treatment with Betaleukin was significantly associated with shorter duration of catarrhal syndrome and decreased resolution terms of lung infiltrates. Usage of Betaleukin was shown to influence the levels of pro- and anti-inflammatory cytokines and interferons. Betaleukin is effective in patients under 50 years old, independent on initial volume of lung infiltrates. Full resolution of pneumonia treated with Betaleukin was observed in patients with initial IL-1β concentrations under 80 pg/ml, or 80-120 pg/ml, and IL-1rа concentrations of 500-1000 pg/ml in blood serum.
format	article
author	L. V. Voloschchuk E. G. Golovacheva A. L. Mushkatina L. V. Osidak P. V. Zarishnyuk A. A. Go
author_facet	L. V. Voloschchuk E. G. Golovacheva A. L. Mushkatina L. V. Osidak P. V. Zarishnyuk A. A. Go
author_sort	L. V. Voloschchuk
title	CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA
title_short	CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA
title_full	CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA
title_fullStr	CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA
title_full_unstemmed	CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA
title_sort	clinical and immunological efficiency of betaleukin in patients with influenza and flu-like diseases complicated by pneumonia
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/c627294486594cb88eaa549352400c37
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CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF BETALEUKIN IN PATIENTS WITH INFLUENZA AND FLU-LIKE DISEASES COMPLICATED BY PNEUMONIA

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