Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
The Paf1 complex (Paf1C) is an elongation factor assembly that forms the interface between transcribing Pol II and chromatin factors. Here the authors describe the architecture of Paf1C and its interface with Pol II, and show that Paf1C is globally required for normal mRNA transcription in yeast.
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Nature Portfolio
2017
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oai:doaj.org-article:c62e62a3bc00493790f327fdb8c7a2562021-12-02T14:41:58ZArchitecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex10.1038/ncomms157412041-1723https://doaj.org/article/c62e62a3bc00493790f327fdb8c7a2562017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15741https://doaj.org/toc/2041-1723The Paf1 complex (Paf1C) is an elongation factor assembly that forms the interface between transcribing Pol II and chromatin factors. Here the authors describe the architecture of Paf1C and its interface with Pol II, and show that Paf1C is globally required for normal mRNA transcription in yeast.Youwei XuCarrie BerneckyChung-Tien LeeKerstin C. MaierBjörn SchwalbDimitry TegunovJürgen M. PlitzkoHenning UrlaubPatrick CramerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Youwei Xu Carrie Bernecky Chung-Tien Lee Kerstin C. Maier Björn Schwalb Dimitry Tegunov Jürgen M. Plitzko Henning Urlaub Patrick Cramer Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex |
description |
The Paf1 complex (Paf1C) is an elongation factor assembly that forms the interface between transcribing Pol II and chromatin factors. Here the authors describe the architecture of Paf1C and its interface with Pol II, and show that Paf1C is globally required for normal mRNA transcription in yeast. |
format |
article |
author |
Youwei Xu Carrie Bernecky Chung-Tien Lee Kerstin C. Maier Björn Schwalb Dimitry Tegunov Jürgen M. Plitzko Henning Urlaub Patrick Cramer |
author_facet |
Youwei Xu Carrie Bernecky Chung-Tien Lee Kerstin C. Maier Björn Schwalb Dimitry Tegunov Jürgen M. Plitzko Henning Urlaub Patrick Cramer |
author_sort |
Youwei Xu |
title |
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex |
title_short |
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex |
title_full |
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex |
title_fullStr |
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex |
title_full_unstemmed |
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex |
title_sort |
architecture of the rna polymerase ii-paf1c-tfiis transcription elongation complex |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c62e62a3bc00493790f327fdb8c7a256 |
work_keys_str_mv |
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1718389835567202304 |