Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex

The Paf1 complex (Paf1C) is an elongation factor assembly that forms the interface between transcribing Pol II and chromatin factors. Here the authors describe the architecture of Paf1C and its interface with Pol II, and show that Paf1C is globally required for normal mRNA transcription in yeast.

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Autores principales: Youwei Xu, Carrie Bernecky, Chung-Tien Lee, Kerstin C. Maier, Björn Schwalb, Dimitry Tegunov, Jürgen M. Plitzko, Henning Urlaub, Patrick Cramer
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c62e62a3bc00493790f327fdb8c7a256
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spelling oai:doaj.org-article:c62e62a3bc00493790f327fdb8c7a2562021-12-02T14:41:58ZArchitecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex10.1038/ncomms157412041-1723https://doaj.org/article/c62e62a3bc00493790f327fdb8c7a2562017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15741https://doaj.org/toc/2041-1723The Paf1 complex (Paf1C) is an elongation factor assembly that forms the interface between transcribing Pol II and chromatin factors. Here the authors describe the architecture of Paf1C and its interface with Pol II, and show that Paf1C is globally required for normal mRNA transcription in yeast.Youwei XuCarrie BerneckyChung-Tien LeeKerstin C. MaierBjörn SchwalbDimitry TegunovJürgen M. PlitzkoHenning UrlaubPatrick CramerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Youwei Xu
Carrie Bernecky
Chung-Tien Lee
Kerstin C. Maier
Björn Schwalb
Dimitry Tegunov
Jürgen M. Plitzko
Henning Urlaub
Patrick Cramer
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
description The Paf1 complex (Paf1C) is an elongation factor assembly that forms the interface between transcribing Pol II and chromatin factors. Here the authors describe the architecture of Paf1C and its interface with Pol II, and show that Paf1C is globally required for normal mRNA transcription in yeast.
format article
author Youwei Xu
Carrie Bernecky
Chung-Tien Lee
Kerstin C. Maier
Björn Schwalb
Dimitry Tegunov
Jürgen M. Plitzko
Henning Urlaub
Patrick Cramer
author_facet Youwei Xu
Carrie Bernecky
Chung-Tien Lee
Kerstin C. Maier
Björn Schwalb
Dimitry Tegunov
Jürgen M. Plitzko
Henning Urlaub
Patrick Cramer
author_sort Youwei Xu
title Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
title_short Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
title_full Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
title_fullStr Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
title_full_unstemmed Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
title_sort architecture of the rna polymerase ii-paf1c-tfiis transcription elongation complex
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c62e62a3bc00493790f327fdb8c7a256
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