Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination

Current treatments of multiple sclerosis are aimed at immunosuppression. Here the authors show that kappa opioid receptor is important for oligodendrocyte differentiation and myelination and the receptor agonists are protective in a mouse model of multiple sclerosis.

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Bibliographic Details
Main Authors: Changsheng Du, Yanhui Duan, Wei Wei, Yingying Cai, Hui Chai, Jie Lv, Xiling Du, Jian Zhu, Xin Xie
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/c63bdc847ad944e9864d75fabc4e718b
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