Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

ABSTRACT Stress granules (SGs) are dynamic cytoplasmic repositories containing translationally silenced mRNAs that assemble upon cellular stress. We recently reported that the SG nucleating protein G3BP1 promotes antiviral activity and is essential in double-stranded RNA-dependent protein kinase (PK...

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Bibliographic Details
Main Authors: Lucas C. Reineke, Nancy Kedersha, Martijn A. Langereis, Frank J. M. van Kuppeveld, Richard E. Lloyd
Format: article
Language:EN
Published: American Society for Microbiology 2015
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Online Access:https://doaj.org/article/c63ece2c93ac4727837c97eb9946fdb6
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