Cardiovascular Protective Effects of Plant Polysaccharides: A Review

Cardiovascular disease is a kind of heart, brain, and blood vessel injury disease by the interaction of various pathological factors. The pathogenesis of cardiovascular disease is complex with various risk factors, including abnormally elevated blood pressure, glucose, and lipid metabolism disorders...

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Autores principales: Xinli Dong, Mengze Zhou, Yehong Li, Yuxin Li, Hui Ji, Qinghua Hu
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/c650ee197c34457aa2410696f704be97
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spelling oai:doaj.org-article:c650ee197c34457aa2410696f704be972021-11-18T06:18:26ZCardiovascular Protective Effects of Plant Polysaccharides: A Review1663-981210.3389/fphar.2021.783641https://doaj.org/article/c650ee197c34457aa2410696f704be972021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fphar.2021.783641/fullhttps://doaj.org/toc/1663-9812Cardiovascular disease is a kind of heart, brain, and blood vessel injury disease by the interaction of various pathological factors. The pathogenesis of cardiovascular disease is complex with various risk factors, including abnormally elevated blood pressure, glucose, and lipid metabolism disorders, atherosclerosis, thrombosis, etc. Plant polysaccharides are a special class of natural products derived from plant resources, which have the characteristics of wide sources, diverse biological activities, and low toxicity or side effects. Many studies have shown that plant polysaccharides improve cardiovascular diseases through various mechanisms such as anti-oxidative stress, restoring the metabolism of biological macromolecules, regulating the apoptosis cascade to reduce cell apoptosis, and inhibiting inflammatory signal pathways to alleviate inflammation. This article reviews the pharmacological effects and protective mechanisms of some plant polysaccharides in modulating the cardiovascular system, which is beneficial for developing more effective drugs with low side effects for management of cardiovascular diseases.Xinli DongXinli DongMengze ZhouYehong LiYehong LiYuxin LiYuxin LiHui JiHui JiQinghua HuQinghua HuFrontiers Media S.A.articleplant polysaccharidescardiovascular diseasespharmacological effectsprotective mechanismslow side effectsTherapeutics. PharmacologyRM1-950ENFrontiers in Pharmacology, Vol 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic plant polysaccharides
cardiovascular diseases
pharmacological effects
protective mechanisms
low side effects
Therapeutics. Pharmacology
RM1-950
spellingShingle plant polysaccharides
cardiovascular diseases
pharmacological effects
protective mechanisms
low side effects
Therapeutics. Pharmacology
RM1-950
Xinli Dong
Xinli Dong
Mengze Zhou
Yehong Li
Yehong Li
Yuxin Li
Yuxin Li
Hui Ji
Hui Ji
Qinghua Hu
Qinghua Hu
Cardiovascular Protective Effects of Plant Polysaccharides: A Review
description Cardiovascular disease is a kind of heart, brain, and blood vessel injury disease by the interaction of various pathological factors. The pathogenesis of cardiovascular disease is complex with various risk factors, including abnormally elevated blood pressure, glucose, and lipid metabolism disorders, atherosclerosis, thrombosis, etc. Plant polysaccharides are a special class of natural products derived from plant resources, which have the characteristics of wide sources, diverse biological activities, and low toxicity or side effects. Many studies have shown that plant polysaccharides improve cardiovascular diseases through various mechanisms such as anti-oxidative stress, restoring the metabolism of biological macromolecules, regulating the apoptosis cascade to reduce cell apoptosis, and inhibiting inflammatory signal pathways to alleviate inflammation. This article reviews the pharmacological effects and protective mechanisms of some plant polysaccharides in modulating the cardiovascular system, which is beneficial for developing more effective drugs with low side effects for management of cardiovascular diseases.
format article
author Xinli Dong
Xinli Dong
Mengze Zhou
Yehong Li
Yehong Li
Yuxin Li
Yuxin Li
Hui Ji
Hui Ji
Qinghua Hu
Qinghua Hu
author_facet Xinli Dong
Xinli Dong
Mengze Zhou
Yehong Li
Yehong Li
Yuxin Li
Yuxin Li
Hui Ji
Hui Ji
Qinghua Hu
Qinghua Hu
author_sort Xinli Dong
title Cardiovascular Protective Effects of Plant Polysaccharides: A Review
title_short Cardiovascular Protective Effects of Plant Polysaccharides: A Review
title_full Cardiovascular Protective Effects of Plant Polysaccharides: A Review
title_fullStr Cardiovascular Protective Effects of Plant Polysaccharides: A Review
title_full_unstemmed Cardiovascular Protective Effects of Plant Polysaccharides: A Review
title_sort cardiovascular protective effects of plant polysaccharides: a review
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/c650ee197c34457aa2410696f704be97
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AT xinlidong cardiovascularprotectiveeffectsofplantpolysaccharidesareview
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AT yehongli cardiovascularprotectiveeffectsofplantpolysaccharidesareview
AT yuxinli cardiovascularprotectiveeffectsofplantpolysaccharidesareview
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