Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Glycoprotein G of vesicular stomatitis virus (VSV) enables viral entry by binding to the major VSV receptor LDL-R. Here the authors present crystal structures of G in complex with two distinct CR domains of LDL-R, identifying structural determinants for VSV infectivity in mammalian and insect cells.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jovan Nikolic, Laura Belot, Hélène Raux, Pierre Legrand, Yves Gaudin, Aurélie A. Albertini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c655891b73d54aeb8adf1a017f3f60af
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c655891b73d54aeb8adf1a017f3f60af
record_format	dspace
spelling	oai:doaj.org-article:c655891b73d54aeb8adf1a017f3f60af2021-12-02T16:49:56ZStructural basis for the recognition of LDL-receptor family members by VSV glycoprotein10.1038/s41467-018-03432-42041-1723https://doaj.org/article/c655891b73d54aeb8adf1a017f3f60af2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03432-4https://doaj.org/toc/2041-1723Glycoprotein G of vesicular stomatitis virus (VSV) enables viral entry by binding to the major VSV receptor LDL-R. Here the authors present crystal structures of G in complex with two distinct CR domains of LDL-R, identifying structural determinants for VSV infectivity in mammalian and insect cells.Jovan NikolicLaura BelotHélène RauxPierre LegrandYves GaudinAurélie A. AlbertiniNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jovan Nikolic Laura Belot Hélène Raux Pierre Legrand Yves Gaudin Aurélie A. Albertini Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
description	Glycoprotein G of vesicular stomatitis virus (VSV) enables viral entry by binding to the major VSV receptor LDL-R. Here the authors present crystal structures of G in complex with two distinct CR domains of LDL-R, identifying structural determinants for VSV infectivity in mammalian and insect cells.
format	article
author	Jovan Nikolic Laura Belot Hélène Raux Pierre Legrand Yves Gaudin Aurélie A. Albertini
author_facet	Jovan Nikolic Laura Belot Hélène Raux Pierre Legrand Yves Gaudin Aurélie A. Albertini
author_sort	Jovan Nikolic
title	Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
title_short	Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
title_full	Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
title_fullStr	Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
title_full_unstemmed	Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
title_sort	structural basis for the recognition of ldl-receptor family members by vsv glycoprotein
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c655891b73d54aeb8adf1a017f3f60af
work_keys_str_mv	AT jovannikolic structuralbasisfortherecognitionofldlreceptorfamilymembersbyvsvglycoprotein AT laurabelot structuralbasisfortherecognitionofldlreceptorfamilymembersbyvsvglycoprotein AT heleneraux structuralbasisfortherecognitionofldlreceptorfamilymembersbyvsvglycoprotein AT pierrelegrand structuralbasisfortherecognitionofldlreceptorfamilymembersbyvsvglycoprotein AT yvesgaudin structuralbasisfortherecognitionofldlreceptorfamilymembersbyvsvglycoprotein AT aurelieaalbertini structuralbasisfortherecognitionofldlreceptorfamilymembersbyvsvglycoprotein
_version_	1718383183241674752

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Ejemplares similares