Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Glycoprotein G of vesicular stomatitis virus (VSV) enables viral entry by binding to the major VSV receptor LDL-R. Here the authors present crystal structures of G in complex with two distinct CR domains of LDL-R, identifying structural determinants for VSV infectivity in mammalian and insect cells.

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Detalles Bibliográficos
Autores principales: Jovan Nikolic, Laura Belot, Hélène Raux, Pierre Legrand, Yves Gaudin, Aurélie A. Albertini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/c655891b73d54aeb8adf1a017f3f60af
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