Gradient light interference microscopy for 3D imaging of unlabeled specimens

Challenges in biological imaging include labeling, photobleaching and phototoxicity, as well as light scattering. Here, Nguyen et al. develop a quantitative phase method that uses low-coherence interferometry for label-free 3D imaging in scattering tissue.

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Autores principales: Tan H. Nguyen, Mikhail E. Kandel, Marcello Rubessa, Matthew B. Wheeler, Gabriel Popescu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c65e37646af14d50945de891b9a135e7
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spelling oai:doaj.org-article:c65e37646af14d50945de891b9a135e72021-12-02T13:57:45ZGradient light interference microscopy for 3D imaging of unlabeled specimens10.1038/s41467-017-00190-72041-1723https://doaj.org/article/c65e37646af14d50945de891b9a135e72017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00190-7https://doaj.org/toc/2041-1723Challenges in biological imaging include labeling, photobleaching and phototoxicity, as well as light scattering. Here, Nguyen et al. develop a quantitative phase method that uses low-coherence interferometry for label-free 3D imaging in scattering tissue.Tan H. NguyenMikhail E. KandelMarcello RubessaMatthew B. WheelerGabriel PopescuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tan H. Nguyen
Mikhail E. Kandel
Marcello Rubessa
Matthew B. Wheeler
Gabriel Popescu
Gradient light interference microscopy for 3D imaging of unlabeled specimens
description Challenges in biological imaging include labeling, photobleaching and phototoxicity, as well as light scattering. Here, Nguyen et al. develop a quantitative phase method that uses low-coherence interferometry for label-free 3D imaging in scattering tissue.
format article
author Tan H. Nguyen
Mikhail E. Kandel
Marcello Rubessa
Matthew B. Wheeler
Gabriel Popescu
author_facet Tan H. Nguyen
Mikhail E. Kandel
Marcello Rubessa
Matthew B. Wheeler
Gabriel Popescu
author_sort Tan H. Nguyen
title Gradient light interference microscopy for 3D imaging of unlabeled specimens
title_short Gradient light interference microscopy for 3D imaging of unlabeled specimens
title_full Gradient light interference microscopy for 3D imaging of unlabeled specimens
title_fullStr Gradient light interference microscopy for 3D imaging of unlabeled specimens
title_full_unstemmed Gradient light interference microscopy for 3D imaging of unlabeled specimens
title_sort gradient light interference microscopy for 3d imaging of unlabeled specimens
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c65e37646af14d50945de891b9a135e7
work_keys_str_mv AT tanhnguyen gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens
AT mikhailekandel gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens
AT marcellorubessa gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens
AT matthewbwheeler gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens
AT gabrielpopescu gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens
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