Gradient light interference microscopy for 3D imaging of unlabeled specimens
Challenges in biological imaging include labeling, photobleaching and phototoxicity, as well as light scattering. Here, Nguyen et al. develop a quantitative phase method that uses low-coherence interferometry for label-free 3D imaging in scattering tissue.
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Nature Portfolio
2017
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oai:doaj.org-article:c65e37646af14d50945de891b9a135e72021-12-02T13:57:45ZGradient light interference microscopy for 3D imaging of unlabeled specimens10.1038/s41467-017-00190-72041-1723https://doaj.org/article/c65e37646af14d50945de891b9a135e72017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00190-7https://doaj.org/toc/2041-1723Challenges in biological imaging include labeling, photobleaching and phototoxicity, as well as light scattering. Here, Nguyen et al. develop a quantitative phase method that uses low-coherence interferometry for label-free 3D imaging in scattering tissue.Tan H. NguyenMikhail E. KandelMarcello RubessaMatthew B. WheelerGabriel PopescuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Tan H. Nguyen Mikhail E. Kandel Marcello Rubessa Matthew B. Wheeler Gabriel Popescu Gradient light interference microscopy for 3D imaging of unlabeled specimens |
description |
Challenges in biological imaging include labeling, photobleaching and phototoxicity, as well as light scattering. Here, Nguyen et al. develop a quantitative phase method that uses low-coherence interferometry for label-free 3D imaging in scattering tissue. |
format |
article |
author |
Tan H. Nguyen Mikhail E. Kandel Marcello Rubessa Matthew B. Wheeler Gabriel Popescu |
author_facet |
Tan H. Nguyen Mikhail E. Kandel Marcello Rubessa Matthew B. Wheeler Gabriel Popescu |
author_sort |
Tan H. Nguyen |
title |
Gradient light interference microscopy for 3D imaging of unlabeled specimens |
title_short |
Gradient light interference microscopy for 3D imaging of unlabeled specimens |
title_full |
Gradient light interference microscopy for 3D imaging of unlabeled specimens |
title_fullStr |
Gradient light interference microscopy for 3D imaging of unlabeled specimens |
title_full_unstemmed |
Gradient light interference microscopy for 3D imaging of unlabeled specimens |
title_sort |
gradient light interference microscopy for 3d imaging of unlabeled specimens |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c65e37646af14d50945de891b9a135e7 |
work_keys_str_mv |
AT tanhnguyen gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens AT mikhailekandel gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens AT marcellorubessa gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens AT matthewbwheeler gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens AT gabrielpopescu gradientlightinterferencemicroscopyfor3dimagingofunlabeledspecimens |
_version_ |
1718392285094215680 |