Eclipta prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities

Eclipta prostrata (L.) L. (Syn.: Eclipta alba (L.) Hassak, Family: Asteraceae) is an important medicinal plant in the tropical and subtropical regions. It is widely used in treating various diseases of skin, liver and stomach in India, Nepal, Bangladesh, and oth...

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Autores principales:	Deepak Timalsina, Hari Prasad Devkota
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Eclipta prostrata</i> <i>Eclipta alba</i> ecalbasaponin hepatoprotective wedelolactone Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/c663b6d7029b4ea98037200bf8546f6b
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id	oai:doaj.org-article:c663b6d7029b4ea98037200bf8546f6b
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spelling	oai:doaj.org-article:c663b6d7029b4ea98037200bf8546f6b2021-11-25T16:54:43Z<i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities10.3390/biom111117382218-273Xhttps://doaj.org/article/c663b6d7029b4ea98037200bf8546f6b2021-11-01T00:00:00Zhttps://www.mdpi.com/2218-273X/11/11/1738https://doaj.org/toc/2218-273X<i>Eclipta prostrata</i> (L.) L. (Syn.: <i>Eclipta alba</i> (L.) Hassak, Family: Asteraceae) is an important medicinal plant in the tropical and subtropical regions. It is widely used in treating various diseases of skin, liver and stomach in India, Nepal, Bangladesh, and other countries. The main aim of this review was to collect and analyze the available information on traditional uses, phytoconstituents, and biological activities of <i>E. prostrata</i>. The scientific information was collected from the online bibliographic databases such as Scopus, MEDLINE/PubMed, Google Scholar, SciFinder, etc. and books and proceedings. The active phytochemicals were coumestan derivatives, phenolic acid derivatives, flavonoids, triterpenoid and steroid saponins, substituted thiophenes, etc. Various extracts and isolated compounds of <i>E. prostrata</i> showed a wide range of biological activities such as antimicrobial, anticancer, hepatoprotective, neuroprotective and hair growth promoting activities. Relatively a few studies have been performed to reveal the exact phytoconstituents responsible for their corresponding pharmacological activities. Future studies should focus on detailed mechanism based studies using animal models and clinical studies.Deepak TimalsinaHari Prasad DevkotaMDPI AGarticle<i>Eclipta prostrata</i><i>Eclipta alba</i>ecalbasaponinhepatoprotectivewedelolactoneMicrobiologyQR1-502ENBiomolecules, Vol 11, Iss 1738, p 1738 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Eclipta prostrata</i> <i>Eclipta alba</i> ecalbasaponin hepatoprotective wedelolactone Microbiology QR1-502
spellingShingle	<i>Eclipta prostrata</i> <i>Eclipta alba</i> ecalbasaponin hepatoprotective wedelolactone Microbiology QR1-502 Deepak Timalsina Hari Prasad Devkota <i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities
description	<i>Eclipta prostrata</i> (L.) L. (Syn.: <i>Eclipta alba</i> (L.) Hassak, Family: Asteraceae) is an important medicinal plant in the tropical and subtropical regions. It is widely used in treating various diseases of skin, liver and stomach in India, Nepal, Bangladesh, and other countries. The main aim of this review was to collect and analyze the available information on traditional uses, phytoconstituents, and biological activities of <i>E. prostrata</i>. The scientific information was collected from the online bibliographic databases such as Scopus, MEDLINE/PubMed, Google Scholar, SciFinder, etc. and books and proceedings. The active phytochemicals were coumestan derivatives, phenolic acid derivatives, flavonoids, triterpenoid and steroid saponins, substituted thiophenes, etc. Various extracts and isolated compounds of <i>E. prostrata</i> showed a wide range of biological activities such as antimicrobial, anticancer, hepatoprotective, neuroprotective and hair growth promoting activities. Relatively a few studies have been performed to reveal the exact phytoconstituents responsible for their corresponding pharmacological activities. Future studies should focus on detailed mechanism based studies using animal models and clinical studies.
format	article
author	Deepak Timalsina Hari Prasad Devkota
author_facet	Deepak Timalsina Hari Prasad Devkota
author_sort	Deepak Timalsina
title	<i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities
title_short	<i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities
title_full	<i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities
title_fullStr	<i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities
title_full_unstemmed	<i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities
title_sort	<i>eclipta prostrata</i> (l.) l. (asteraceae): ethnomedicinal uses, chemical constituents, and biological activities
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c663b6d7029b4ea98037200bf8546f6b
work_keys_str_mv	AT deepaktimalsina iecliptaprostrataillasteraceaeethnomedicinaluseschemicalconstituentsandbiologicalactivities AT hariprasaddevkota iecliptaprostrataillasteraceaeethnomedicinaluseschemicalconstituentsandbiologicalactivities
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<i>Eclipta prostrata</i> (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities

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