Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection

Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection

Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.

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Detalles Bibliográficos
Autores principales: Guillaume F. Combes, Hussein Fakhouri, Christophe Moulin, Marion Girod, Franck Bertorelle, Srestha Basu, Romain Ladouce, Martina Perić Bakulić, Željka Sanader Maršić, Isabelle Russier-Antoine, Pierre-François Brevet, Philippe Dugourd, Anita Krisko, Katarina Trajković, Miroslav Radman, Vlasta Bonačić-Koutecký, Rodolphe Antoine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/c68605eea77f48788ddfb6619a9923c3
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Descripción
Sumario:Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.

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