Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection

Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.

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Autores principales: Guillaume F. Combes, Hussein Fakhouri, Christophe Moulin, Marion Girod, Franck Bertorelle, Srestha Basu, Romain Ladouce, Martina Perić Bakulić, Željka Sanader Maršić, Isabelle Russier-Antoine, Pierre-François Brevet, Philippe Dugourd, Anita Krisko, Katarina Trajković, Miroslav Radman, Vlasta Bonačić-Koutecký, Rodolphe Antoine
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c68605eea77f48788ddfb6619a9923c3
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spelling oai:doaj.org-article:c68605eea77f48788ddfb6619a9923c32021-12-02T17:15:32ZFunctionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection10.1038/s42004-021-00497-z2399-3669https://doaj.org/article/c68605eea77f48788ddfb6619a9923c32021-05-01T00:00:00Zhttps://doi.org/10.1038/s42004-021-00497-zhttps://doaj.org/toc/2399-3669Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.Guillaume F. CombesHussein FakhouriChristophe MoulinMarion GirodFranck BertorelleSrestha BasuRomain LadouceMartina Perić BakulićŽeljka Sanader MaršićIsabelle Russier-AntoinePierre-François BrevetPhilippe DugourdAnita KriskoKatarina TrajkovićMiroslav RadmanVlasta Bonačić-KouteckýRodolphe AntoineNature PortfolioarticleChemistryQD1-999ENCommunications Chemistry, Vol 4, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Chemistry
QD1-999
spellingShingle Chemistry
QD1-999
Guillaume F. Combes
Hussein Fakhouri
Christophe Moulin
Marion Girod
Franck Bertorelle
Srestha Basu
Romain Ladouce
Martina Perić Bakulić
Željka Sanader Maršić
Isabelle Russier-Antoine
Pierre-François Brevet
Philippe Dugourd
Anita Krisko
Katarina Trajković
Miroslav Radman
Vlasta Bonačić-Koutecký
Rodolphe Antoine
Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
description Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.
format article
author Guillaume F. Combes
Hussein Fakhouri
Christophe Moulin
Marion Girod
Franck Bertorelle
Srestha Basu
Romain Ladouce
Martina Perić Bakulić
Željka Sanader Maršić
Isabelle Russier-Antoine
Pierre-François Brevet
Philippe Dugourd
Anita Krisko
Katarina Trajković
Miroslav Radman
Vlasta Bonačić-Koutecký
Rodolphe Antoine
author_facet Guillaume F. Combes
Hussein Fakhouri
Christophe Moulin
Marion Girod
Franck Bertorelle
Srestha Basu
Romain Ladouce
Martina Perić Bakulić
Željka Sanader Maršić
Isabelle Russier-Antoine
Pierre-François Brevet
Philippe Dugourd
Anita Krisko
Katarina Trajković
Miroslav Radman
Vlasta Bonačić-Koutecký
Rodolphe Antoine
author_sort Guillaume F. Combes
title Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
title_short Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
title_full Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
title_fullStr Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
title_full_unstemmed Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
title_sort functionalized au15 nanoclusters as luminescent probes for protein carbonylation detection
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c68605eea77f48788ddfb6619a9923c3
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