A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation

Transcription is globally repressed in early stage of embryo development, but a set of genes including pri-miR-430 and zinc finger genes is known to escape the repression. Here the authors image the very first transcriptional activities in the living zebra fish embryo, demonstrating a cell cycle-coo...

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Autores principales: Yavor Hadzhiev, Haseeb K. Qureshi, Lucy Wheatley, Ledean Cooper, Aleksandra Jasiulewicz, Huy Van Nguyen, Joseph W. Wragg, Divyasree Poovathumkadavil, Sascha Conic, Sarah Bajan, Attila Sik, György Hutvàgner, Làszlò Tora, Agnieszka Gambus, John S. Fossey, Ferenc Müller
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c687a4f0c35544f7aae2b16326e305e8
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spelling oai:doaj.org-article:c687a4f0c35544f7aae2b16326e305e82021-12-02T16:58:28ZA cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation10.1038/s41467-019-08487-52041-1723https://doaj.org/article/c687a4f0c35544f7aae2b16326e305e82019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08487-5https://doaj.org/toc/2041-1723Transcription is globally repressed in early stage of embryo development, but a set of genes including pri-miR-430 and zinc finger genes is known to escape the repression. Here the authors image the very first transcriptional activities in the living zebra fish embryo, demonstrating a cell cycle-coordinated polymerase II transcription compartment.Yavor HadzhievHaseeb K. QureshiLucy WheatleyLedean CooperAleksandra JasiulewiczHuy Van NguyenJoseph W. WraggDivyasree PoovathumkadavilSascha ConicSarah BajanAttila SikGyörgy HutvàgnerLàszlò ToraAgnieszka GambusJohn S. FosseyFerenc MüllerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yavor Hadzhiev
Haseeb K. Qureshi
Lucy Wheatley
Ledean Cooper
Aleksandra Jasiulewicz
Huy Van Nguyen
Joseph W. Wragg
Divyasree Poovathumkadavil
Sascha Conic
Sarah Bajan
Attila Sik
György Hutvàgner
Làszlò Tora
Agnieszka Gambus
John S. Fossey
Ferenc Müller
A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
description Transcription is globally repressed in early stage of embryo development, but a set of genes including pri-miR-430 and zinc finger genes is known to escape the repression. Here the authors image the very first transcriptional activities in the living zebra fish embryo, demonstrating a cell cycle-coordinated polymerase II transcription compartment.
format article
author Yavor Hadzhiev
Haseeb K. Qureshi
Lucy Wheatley
Ledean Cooper
Aleksandra Jasiulewicz
Huy Van Nguyen
Joseph W. Wragg
Divyasree Poovathumkadavil
Sascha Conic
Sarah Bajan
Attila Sik
György Hutvàgner
Làszlò Tora
Agnieszka Gambus
John S. Fossey
Ferenc Müller
author_facet Yavor Hadzhiev
Haseeb K. Qureshi
Lucy Wheatley
Ledean Cooper
Aleksandra Jasiulewicz
Huy Van Nguyen
Joseph W. Wragg
Divyasree Poovathumkadavil
Sascha Conic
Sarah Bajan
Attila Sik
György Hutvàgner
Làszlò Tora
Agnieszka Gambus
John S. Fossey
Ferenc Müller
author_sort Yavor Hadzhiev
title A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
title_short A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
title_full A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
title_fullStr A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
title_full_unstemmed A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
title_sort cell cycle-coordinated polymerase ii transcription compartment encompasses gene expression before global genome activation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/c687a4f0c35544f7aae2b16326e305e8
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