Liver governs adipose remodelling via extracellular vesicles in response to lipid overload

Extracellular vesicles (EVs) containing miRNAs or proteins can coordinate metabolic responses between tissues. Here the authors demonstrate that during lipid overload, the liver secretes miRNA-containing EVs through a Ggpps-Rab27 dependent mechanism, which controls adipose tissue lipid storage capac...

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Bibliographic Details
Main Authors: Yue Zhao, Meng-Fei Zhao, Shan Jiang, Jing Wu, Jia Liu, Xian-Wen Yuan, Di Shen, Jing-Zi Zhang, Nan Zhou, Jian He, Lei Fang, Xi-Tai Sun, Bin Xue, Chao-Jun Li
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/c690879c6ccc460ba0a45d4204010083
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