Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications

Tetraspanins are transmembrane proteins expressed in a multitude of cells throughout the organism. They contribute to many processes that surround cell–cell interactions and are associated with the progress of some diseases, including cancer. Their crucial role in cell physiology is often understate...

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Autores principales:	Stefan Titu, Cristiana Maria Grapa, Teodora Mocan, Ovidiu Balacescu, Alexandru Irimie
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	tetraspanins physiology colorectal cancer nanotechnology Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/c695b645149148f1ad1ef237ea211ead
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spelling	oai:doaj.org-article:c695b645149148f1ad1ef237ea211ead2021-11-25T17:02:23ZTetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications10.3390/cancers132256622072-6694https://doaj.org/article/c695b645149148f1ad1ef237ea211ead2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/22/5662https://doaj.org/toc/2072-6694Tetraspanins are transmembrane proteins expressed in a multitude of cells throughout the organism. They contribute to many processes that surround cell–cell interactions and are associated with the progress of some diseases, including cancer. Their crucial role in cell physiology is often understated. Furthermore, recent studies have shown their great potential in being used as targeting molecules. Data have suggested the potential of tetraspanins as a targeting vector for nanomediated distribution and delivery for colorectal cancer applications. Our aim is to provide a review on the important part that tetraspanins play in the human organism and highlight their potential use for drug delivery systems using nanotechnology.Stefan TituCristiana Maria GrapaTeodora MocanOvidiu BalacescuAlexandru IrimieMDPI AGarticletetraspaninsphysiologycolorectal cancernanotechnologyNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5662, p 5662 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	tetraspanins physiology colorectal cancer nanotechnology Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	tetraspanins physiology colorectal cancer nanotechnology Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Stefan Titu Cristiana Maria Grapa Teodora Mocan Ovidiu Balacescu Alexandru Irimie Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications
description	Tetraspanins are transmembrane proteins expressed in a multitude of cells throughout the organism. They contribute to many processes that surround cell–cell interactions and are associated with the progress of some diseases, including cancer. Their crucial role in cell physiology is often understated. Furthermore, recent studies have shown their great potential in being used as targeting molecules. Data have suggested the potential of tetraspanins as a targeting vector for nanomediated distribution and delivery for colorectal cancer applications. Our aim is to provide a review on the important part that tetraspanins play in the human organism and highlight their potential use for drug delivery systems using nanotechnology.
format	article
author	Stefan Titu Cristiana Maria Grapa Teodora Mocan Ovidiu Balacescu Alexandru Irimie
author_facet	Stefan Titu Cristiana Maria Grapa Teodora Mocan Ovidiu Balacescu Alexandru Irimie
author_sort	Stefan Titu
title	Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications
title_short	Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications
title_full	Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications
title_fullStr	Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications
title_full_unstemmed	Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications
title_sort	tetraspanins: physiology, colorectal cancer development, and nanomediated applications
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c695b645149148f1ad1ef237ea211ead
work_keys_str_mv	AT stefantitu tetraspaninsphysiologycolorectalcancerdevelopmentandnanomediatedapplications AT cristianamariagrapa tetraspaninsphysiologycolorectalcancerdevelopmentandnanomediatedapplications AT teodoramocan tetraspaninsphysiologycolorectalcancerdevelopmentandnanomediatedapplications AT ovidiubalacescu tetraspaninsphysiologycolorectalcancerdevelopmentandnanomediatedapplications AT alexandruirimie tetraspaninsphysiologycolorectalcancerdevelopmentandnanomediatedapplications
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Tetraspanins: Physiology, Colorectal Cancer Development, and Nanomediated Applications

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