Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time

Real time cellular fluorescence imaging requires a probe that displays high degrees of localisation, low toxicity and good photostability. Here, the authors report a near infrared fluorophore that displays pH-sensitive fluorescence based on phenol/phenolate interconversion, showing real time imaging...

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Autores principales: Marco Grossi, Marina Morgunova, Shane Cheung, Dimitri Scholz, Emer Conroy, Marta Terrile, Angela Panarella, Jeremy C. Simpson, William M. Gallagher, Donal F. O’Shea
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c69ff08a7a7d403082a12a213aecbc3d
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spelling oai:doaj.org-article:c69ff08a7a7d403082a12a213aecbc3d2021-12-02T16:57:49ZLysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time10.1038/ncomms108552041-1723https://doaj.org/article/c69ff08a7a7d403082a12a213aecbc3d2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10855https://doaj.org/toc/2041-1723Real time cellular fluorescence imaging requires a probe that displays high degrees of localisation, low toxicity and good photostability. Here, the authors report a near infrared fluorophore that displays pH-sensitive fluorescence based on phenol/phenolate interconversion, showing real time imaging of cellular processes.Marco GrossiMarina MorgunovaShane CheungDimitri ScholzEmer ConroyMarta TerrileAngela PanarellaJeremy C. SimpsonWilliam M. GallagherDonal F. O’SheaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marco Grossi
Marina Morgunova
Shane Cheung
Dimitri Scholz
Emer Conroy
Marta Terrile
Angela Panarella
Jeremy C. Simpson
William M. Gallagher
Donal F. O’Shea
Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time
description Real time cellular fluorescence imaging requires a probe that displays high degrees of localisation, low toxicity and good photostability. Here, the authors report a near infrared fluorophore that displays pH-sensitive fluorescence based on phenol/phenolate interconversion, showing real time imaging of cellular processes.
format article
author Marco Grossi
Marina Morgunova
Shane Cheung
Dimitri Scholz
Emer Conroy
Marta Terrile
Angela Panarella
Jeremy C. Simpson
William M. Gallagher
Donal F. O’Shea
author_facet Marco Grossi
Marina Morgunova
Shane Cheung
Dimitri Scholz
Emer Conroy
Marta Terrile
Angela Panarella
Jeremy C. Simpson
William M. Gallagher
Donal F. O’Shea
author_sort Marco Grossi
title Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time
title_short Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time
title_full Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time
title_fullStr Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time
title_full_unstemmed Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time
title_sort lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c69ff08a7a7d403082a12a213aecbc3d
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