Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry

Taxus species have attracted much attention for their potency in cancer treatment. However, investigating the bioactivities of Taxus species is a complex task, due to their diversity, slow growth, and endangered state. The most important Taxus species in China are Taxus chinensis (T. chinensis), Tax...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Zhang Shuqiang, Lu Xueyan, Zheng Tianyao, Guo Xiaorui, Chen Qi, Tang Zhonghua
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	taxus chinensis taxus cuspidata taxus × media bioactivities gas chromatography-mass spectrometry Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c6b5e686a60847a0bc1c39709f951f45
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c6b5e686a60847a0bc1c39709f951f45
record_format	dspace
spelling	oai:doaj.org-article:c6b5e686a60847a0bc1c39709f951f452021-12-05T14:10:41ZInvestigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry2391-541210.1515/biol-2021-0032https://doaj.org/article/c6b5e686a60847a0bc1c39709f951f452021-03-01T00:00:00Zhttps://doi.org/10.1515/biol-2021-0032https://doaj.org/toc/2391-5412Taxus species have attracted much attention for their potency in cancer treatment. However, investigating the bioactivities of Taxus species is a complex task, due to their diversity, slow growth, and endangered state. The most important Taxus species in China are Taxus chinensis (T. chinensis), Taxus cuspidata (T. cuspidata), and Taxus × media (T. media), which mainly grow in the northeastern region. This article probes deep into the differences among the leaves of T. chinensis, T. cuspidata, and T. media, with the aid of gas chromatography-mass spectrometry (GC-MS). Through GC-MS, 162 compounds were detected in the samples and found to contain 35 bioactive metabolites. On this basis, 20 metabolites with significant bioactivities (antibiotic, antioxidant, anticancer, and antiaging effects) were identified via unsupervised learning of principal component analysis and supervised learning of partial least squares-discriminant analysis. The results show that T. media has the most prominent antibiotic, antioxidant, and anticancer effects, while T. cuspidata has the most diverse and abundant metabolites that slow down aging.Zhang ShuqiangLu XueyanZheng TianyaoGuo XiaoruiChen QiTang ZhonghuaDe Gruyterarticletaxus chinensistaxus cuspidatataxus × mediabioactivitiesgas chromatography-mass spectrometryBiology (General)QH301-705.5ENOpen Life Sciences, Vol 16, Iss 1, Pp 287-296 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	taxus chinensis taxus cuspidata taxus × media bioactivities gas chromatography-mass spectrometry Biology (General) QH301-705.5
spellingShingle	taxus chinensis taxus cuspidata taxus × media bioactivities gas chromatography-mass spectrometry Biology (General) QH301-705.5 Zhang Shuqiang Lu Xueyan Zheng Tianyao Guo Xiaorui Chen Qi Tang Zhonghua Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
description	Taxus species have attracted much attention for their potency in cancer treatment. However, investigating the bioactivities of Taxus species is a complex task, due to their diversity, slow growth, and endangered state. The most important Taxus species in China are Taxus chinensis (T. chinensis), Taxus cuspidata (T. cuspidata), and Taxus × media (T. media), which mainly grow in the northeastern region. This article probes deep into the differences among the leaves of T. chinensis, T. cuspidata, and T. media, with the aid of gas chromatography-mass spectrometry (GC-MS). Through GC-MS, 162 compounds were detected in the samples and found to contain 35 bioactive metabolites. On this basis, 20 metabolites with significant bioactivities (antibiotic, antioxidant, anticancer, and antiaging effects) were identified via unsupervised learning of principal component analysis and supervised learning of partial least squares-discriminant analysis. The results show that T. media has the most prominent antibiotic, antioxidant, and anticancer effects, while T. cuspidata has the most diverse and abundant metabolites that slow down aging.
format	article
author	Zhang Shuqiang Lu Xueyan Zheng Tianyao Guo Xiaorui Chen Qi Tang Zhonghua
author_facet	Zhang Shuqiang Lu Xueyan Zheng Tianyao Guo Xiaorui Chen Qi Tang Zhonghua
author_sort	Zhang Shuqiang
title	Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
title_short	Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
title_full	Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
title_fullStr	Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
title_full_unstemmed	Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
title_sort	investigation of bioactivities of taxus chinensis, taxus cuspidata, and taxus × media by gas chromatography-mass spectrometry
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/c6b5e686a60847a0bc1c39709f951f45
work_keys_str_mv	AT zhangshuqiang investigationofbioactivitiesoftaxuschinensistaxuscuspidataandtaxusmediabygaschromatographymassspectrometry AT luxueyan investigationofbioactivitiesoftaxuschinensistaxuscuspidataandtaxusmediabygaschromatographymassspectrometry AT zhengtianyao investigationofbioactivitiesoftaxuschinensistaxuscuspidataandtaxusmediabygaschromatographymassspectrometry AT guoxiaorui investigationofbioactivitiesoftaxuschinensistaxuscuspidataandtaxusmediabygaschromatographymassspectrometry AT chenqi investigationofbioactivitiesoftaxuschinensistaxuscuspidataandtaxusmediabygaschromatographymassspectrometry AT tangzhonghua investigationofbioactivitiesoftaxuschinensistaxuscuspidataandtaxusmediabygaschromatographymassspectrometry
_version_	1718371865454444544

Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry

Ejemplares similares