SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity

Regulation of Yes-associated protein (YAP) through the Hippo pathway is well established, but its Hippo-independent regulation remains to be elucidated. Here, the authors show that non-proteolytic ubiquitination presents another means of YAP regulation, promoting its nuclear localization and activit...

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Autores principales:	Fan Yao, Zhicheng Zhou, Jongchan Kim, Qinglei Hang, Zhenna Xiao, Baochau N. Ton, Liang Chang, Na Liu, Liyong Zeng, Wenqi Wang, Yumeng Wang, Peijing Zhang, Xiaoyu Hu, Xiaohua Su, Han Liang, Yutong Sun, Li Ma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c6c5c3f681fa48b9a88a52e4fc86fcb8
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spelling	oai:doaj.org-article:c6c5c3f681fa48b9a88a52e4fc86fcb82021-12-02T15:33:35ZSKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity10.1038/s41467-018-04620-y2041-1723https://doaj.org/article/c6c5c3f681fa48b9a88a52e4fc86fcb82018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04620-yhttps://doaj.org/toc/2041-1723Regulation of Yes-associated protein (YAP) through the Hippo pathway is well established, but its Hippo-independent regulation remains to be elucidated. Here, the authors show that non-proteolytic ubiquitination presents another means of YAP regulation, promoting its nuclear localization and activity.Fan YaoZhicheng ZhouJongchan KimQinglei HangZhenna XiaoBaochau N. TonLiang ChangNa LiuLiyong ZengWenqi WangYumeng WangPeijing ZhangXiaoyu HuXiaohua SuHan LiangYutong SunLi MaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fan Yao Zhicheng Zhou Jongchan Kim Qinglei Hang Zhenna Xiao Baochau N. Ton Liang Chang Na Liu Liyong Zeng Wenqi Wang Yumeng Wang Peijing Zhang Xiaoyu Hu Xiaohua Su Han Liang Yutong Sun Li Ma SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
description	Regulation of Yes-associated protein (YAP) through the Hippo pathway is well established, but its Hippo-independent regulation remains to be elucidated. Here, the authors show that non-proteolytic ubiquitination presents another means of YAP regulation, promoting its nuclear localization and activity.
format	article
author	Fan Yao Zhicheng Zhou Jongchan Kim Qinglei Hang Zhenna Xiao Baochau N. Ton Liang Chang Na Liu Liyong Zeng Wenqi Wang Yumeng Wang Peijing Zhang Xiaoyu Hu Xiaohua Su Han Liang Yutong Sun Li Ma
author_facet	Fan Yao Zhicheng Zhou Jongchan Kim Qinglei Hang Zhenna Xiao Baochau N. Ton Liang Chang Na Liu Liyong Zeng Wenqi Wang Yumeng Wang Peijing Zhang Xiaoyu Hu Xiaohua Su Han Liang Yutong Sun Li Ma
author_sort	Fan Yao
title	SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
title_short	SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
title_full	SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
title_fullStr	SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
title_full_unstemmed	SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
title_sort	skp2- and otud1-regulated non-proteolytic ubiquitination of yap promotes yap nuclear localization and activity
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c6c5c3f681fa48b9a88a52e4fc86fcb8
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SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity

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