Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature

The risk of drug interaction (DI), especially in the hospital setting, increases along with the number of drugs used by the patient. Studies that evaluate drug interactions based on patient prescriptions are therefore useful to know this risk and guide strategies to improve drug use. The present st...

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Autores principales:	Adriana Tiemi Yamagata, Roberto Mauro Coelho Barcelos Júnior, Dayani Galato, Micheline Marie Milward De Azevedo Meiners, Emília Vitória Da Silva
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2019
Materias:	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/c6d7066b9e3049619d450efed27100e1
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spelling	oai:doaj.org-article:c6d7066b9e3049619d450efed27100e12021-11-28T02:46:24ZProfile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature10.30968/rbfhss.2018.094.0032179-59242316-7750https://doaj.org/article/c6d7066b9e3049619d450efed27100e12019-11-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/386https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 The risk of drug interaction (DI), especially in the hospital setting, increases along with the number of drugs used by the patient. Studies that evaluate drug interactions based on patient prescriptions are therefore useful to know this risk and guide strategies to improve drug use. The present study is aimed to identify studies that evaluated DI in patients of Brazilian hospitals. As of bibliographic search in several databases, we collected articles describing prescribing evaluations which focused on the analysis and identification of drug interactions in Brazilian hospitals. The search was conducted in 2017 and there was no restriction of publication time. Of a total of 273 articles retrieved, 23 were included for analysis. Most was published after 2010, and the predominant design was cross-sectional studies. The Micromedex® database was the most used to categorize the interactions, and midazolam and fentanyl was the most commonly reported potential DI in the studies. The results may guide futures research which should assess the real harm of IMP in patients and, then, promote the rational use of drugs. Adriana Tiemi YamagataRoberto Mauro Coelho Barcelos JúniorDayani GalatoMicheline Marie Milward De Azevedo MeinersEmília Vitória Da SilvaSociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 9, Iss 4 (2019)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Adriana Tiemi Yamagata Roberto Mauro Coelho Barcelos Júnior Dayani Galato Micheline Marie Milward De Azevedo Meiners Emília Vitória Da Silva Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature
description	The risk of drug interaction (DI), especially in the hospital setting, increases along with the number of drugs used by the patient. Studies that evaluate drug interactions based on patient prescriptions are therefore useful to know this risk and guide strategies to improve drug use. The present study is aimed to identify studies that evaluated DI in patients of Brazilian hospitals. As of bibliographic search in several databases, we collected articles describing prescribing evaluations which focused on the analysis and identification of drug interactions in Brazilian hospitals. The search was conducted in 2017 and there was no restriction of publication time. Of a total of 273 articles retrieved, 23 were included for analysis. Most was published after 2010, and the predominant design was cross-sectional studies. The Micromedex® database was the most used to categorize the interactions, and midazolam and fentanyl was the most commonly reported potential DI in the studies. The results may guide futures research which should assess the real harm of IMP in patients and, then, promote the rational use of drugs.
format	article
author	Adriana Tiemi Yamagata Roberto Mauro Coelho Barcelos Júnior Dayani Galato Micheline Marie Milward De Azevedo Meiners Emília Vitória Da Silva
author_facet	Adriana Tiemi Yamagata Roberto Mauro Coelho Barcelos Júnior Dayani Galato Micheline Marie Milward De Azevedo Meiners Emília Vitória Da Silva
author_sort	Adriana Tiemi Yamagata
title	Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature
title_short	Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature
title_full	Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature
title_fullStr	Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature
title_full_unstemmed	Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature
title_sort	profile of studies of potential drug interactions in brazilian hospitals: an integrative review of the literature
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2019
url	https://doaj.org/article/c6d7066b9e3049619d450efed27100e1
work_keys_str_mv	AT adrianatiemiyamagata profileofstudiesofpotentialdruginteractionsinbrazilianhospitalsanintegrativereviewoftheliterature AT robertomaurocoelhobarcelosjunior profileofstudiesofpotentialdruginteractionsinbrazilianhospitalsanintegrativereviewoftheliterature AT dayanigalato profileofstudiesofpotentialdruginteractionsinbrazilianhospitalsanintegrativereviewoftheliterature AT michelinemariemilwarddeazevedomeiners profileofstudiesofpotentialdruginteractionsinbrazilianhospitalsanintegrativereviewoftheliterature AT emiliavitoriadasilva profileofstudiesofpotentialdruginteractionsinbrazilianhospitalsanintegrativereviewoftheliterature
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Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature

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