Transcriptomic Analysis of <named-content content-type="genus-species">Streptococcus pyogenes</named-content> Colonizing the Vaginal Mucosa Identifies <italic toggle="yes">hupY</italic>, an MtsR-Regulated Adhesin Involved in Heme Utilization

Transcriptomic Analysis of <named-content content-type="genus-species">Streptococcus pyogenes</named-content> Colonizing the Vaginal Mucosa Identifies <italic toggle="yes">hupY</italic>, an MtsR-Regulated Adhesin Involved in Heme Utilization

ABSTRACT Streptococcus pyogenes (group A streptococcus [GAS]) is a serious human pathogen with the ability to colonize mucosal surfaces such as the nasopharynx and vaginal tract, often leading to infections such as pharyngitis and vulvovaginitis. We present genome-wide transcriptome sequencing (RNAS...

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Autores principales: Laura C. C. Cook, Nilanjana Chatterjee, Yan Li, Jorge Andrade, Michael J. Federle, Zehava Eichenbaum
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
colonization
Streptococcus
adherence
heme
iron uptake
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/c6d79089914746b8b2256d0f0e6bd126
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