Comparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique

Background: Pterygium is a fibrovascular tissue that abnormally invades the cornea from the conjunctiva. Aim of the work: Comparison Bare sclera technique of pterygium excision immediately after injecting it with MMC and conjunctival autografting without using MMC regarding recurrence rate and other...

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Autor principal: Sayed El-Sayed
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Publicado: Al-Azhar University, Faculty of Medicine (Damietta) 2021
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spelling oai:doaj.org-article:c6e2ababdd2347998eafb5cf9b359ca22021-12-02T14:06:31ZComparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique2636-41742682-378010.21608/ijma.2020.45799.1191https://doaj.org/article/c6e2ababdd2347998eafb5cf9b359ca22021-01-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_130874_ff117aee7f2e4c28da22c8068f90ce07.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Pterygium is a fibrovascular tissue that abnormally invades the cornea from the conjunctiva. Aim of the work: Comparison Bare sclera technique of pterygium excision immediately after injecting it with MMC and conjunctival autografting without using MMC regarding recurrence rate and other complications. Methods: This prospective interventional study included 40 cases of pterygia from September 2017 to March 2019. cases were divided into two groups: Group 1 included 20 eyes received 0.1 ml [0.01%] of intrapterygial mitomycin-C [MMC] injection, then excision with bare scleral Group 2 included 20 eyes with simple excision then covering the bare sclera with a conjunctival autograft from superior bulbar conjunctiva. Results: The mean age was 45.175 and 45.4 years in Group 1 and 2, respectively, [P = .527]. There were 7 [35%] males and 13 [65%] females in Group 1 and 8 [40%] males and 12 [60%] females in Group 2 [P = .744]. The regression rate was 5% in each Groups [P = 1]. Postoperatively, scleral hypo vascularity occurred in 5 eyes [25%] in Group 1 while never in Group 2 [P = .009]. Graft necrosis noticed in 2 cases [10%] in group 2. Conclusion: Both techniques resulted in a negligible [5%] recurrence rate. Although conjunctival graft with a significant reduction of complications as scleral hypo vascularity but with more surgical time.Sayed El-SayedAl-Azhar University, Faculty of Medicine (Damietta)articleconjunctival graftintrapterygial injectionmitomycin cpterygiumMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 1, Pp 1145-1151 (2021)
institution DOAJ
collection DOAJ
language EN
topic conjunctival graft
intrapterygial injection
mitomycin c
pterygium
Medicine (General)
R5-920
spellingShingle conjunctival graft
intrapterygial injection
mitomycin c
pterygium
Medicine (General)
R5-920
Sayed El-Sayed
Comparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique
description Background: Pterygium is a fibrovascular tissue that abnormally invades the cornea from the conjunctiva. Aim of the work: Comparison Bare sclera technique of pterygium excision immediately after injecting it with MMC and conjunctival autografting without using MMC regarding recurrence rate and other complications. Methods: This prospective interventional study included 40 cases of pterygia from September 2017 to March 2019. cases were divided into two groups: Group 1 included 20 eyes received 0.1 ml [0.01%] of intrapterygial mitomycin-C [MMC] injection, then excision with bare scleral Group 2 included 20 eyes with simple excision then covering the bare sclera with a conjunctival autograft from superior bulbar conjunctiva. Results: The mean age was 45.175 and 45.4 years in Group 1 and 2, respectively, [P = .527]. There were 7 [35%] males and 13 [65%] females in Group 1 and 8 [40%] males and 12 [60%] females in Group 2 [P = .744]. The regression rate was 5% in each Groups [P = 1]. Postoperatively, scleral hypo vascularity occurred in 5 eyes [25%] in Group 1 while never in Group 2 [P = .009]. Graft necrosis noticed in 2 cases [10%] in group 2. Conclusion: Both techniques resulted in a negligible [5%] recurrence rate. Although conjunctival graft with a significant reduction of complications as scleral hypo vascularity but with more surgical time.
format article
author Sayed El-Sayed
author_facet Sayed El-Sayed
author_sort Sayed El-Sayed
title Comparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique
title_short Comparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique
title_full Comparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique
title_fullStr Comparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique
title_full_unstemmed Comparison Study between Intralesional Injection of MMC with Bare Sclera Excision of Pterygium and Conjunctiva Auto Grafting Technique
title_sort comparison study between intralesional injection of mmc with bare sclera excision of pterygium and conjunctiva auto grafting technique
publisher Al-Azhar University, Faculty of Medicine (Damietta)
publishDate 2021
url https://doaj.org/article/c6e2ababdd2347998eafb5cf9b359ca2
work_keys_str_mv AT sayedelsayed comparisonstudybetweenintralesionalinjectionofmmcwithbarescleraexcisionofpterygiumandconjunctivaautograftingtechnique
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