Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis

Purpose: To evaluate corneal elevation changes in patients with allergic conjunctivitis (AC) and to analyze their correlations with ocular allergy signs and corneal biomechanical alterations.Methods: Thirty patients (30 eyes) with AC and twenty normal subjects (20 eyes) were included in this prospec...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Qian Wang, Fei Yu, Ziqing Feng, Weihua Li, Naiyang Li, Xinyue Du, Xuan Zhao, Saiqun Li, Jin Yuan
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	allergic conjunctivitis corneal tomography corneal surface elevation corneal posterior surface corneal biomechanics Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/c6e53847f46349ac8031fc0558c3093e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c6e53847f46349ac8031fc0558c3093e
record_format	dspace
spelling	oai:doaj.org-article:c6e53847f46349ac8031fc0558c3093e2021-11-30T16:53:26ZChanges in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis2296-858X10.3389/fmed.2021.788302https://doaj.org/article/c6e53847f46349ac8031fc0558c3093e2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.788302/fullhttps://doaj.org/toc/2296-858XPurpose: To evaluate corneal elevation changes in patients with allergic conjunctivitis (AC) and to analyze their correlations with ocular allergy signs and corneal biomechanical alterations.Methods: Thirty patients (30 eyes) with AC and twenty normal subjects (20 eyes) were included in this prospective study. All participants underwent a complete ocular examination, including corneal tomography by Pentacam and corneal biomechanics evaluation by Corvis ST. AC patients were evaluated for their eye rubbing frequency and ocular allergic signs.Results: The elevation at the thinnest location (TE) and the central location (CE), the elevation difference at the thinnest location (TED) and the central location (CED), and the mean value of elevation difference in the central 4 mm zoom (MED) of both the anterior and posterior corneal surface were significantly higher in the AC group than in the normal group (p < 0.05 for all). In AC patients, only anterior corneal elevation parameters were positively correlated with eye rubbing frequency and ocular allergy sign severity (p < 0.05 for all), while the tomography and biomechanical index (TBI) was positively correlated with the elevation parameters of both the anterior and posterior corneal surfaces (p < 0.05 for all).Conclusion: AC patients carry an increased risk of corneal ectasia. Posterior corneal elevation parameters are sensitive and reliable predictors of keratoconus (KC) risk in AC patients.Clinical Trial Registration:https://clinicaltrials.gov/ct2/show/NCT04299399, identifier [NCT04299399].Qian WangFei YuZiqing FengWeihua LiNaiyang LiXinyue DuXuan ZhaoSaiqun LiJin YuanFrontiers Media S.A.articleallergic conjunctivitiscorneal tomographycorneal surface elevationcorneal posterior surfacecorneal biomechanicsMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	allergic conjunctivitis corneal tomography corneal surface elevation corneal posterior surface corneal biomechanics Medicine (General) R5-920
spellingShingle	allergic conjunctivitis corneal tomography corneal surface elevation corneal posterior surface corneal biomechanics Medicine (General) R5-920 Qian Wang Fei Yu Ziqing Feng Weihua Li Naiyang Li Xinyue Du Xuan Zhao Saiqun Li Jin Yuan Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis
description	Purpose: To evaluate corneal elevation changes in patients with allergic conjunctivitis (AC) and to analyze their correlations with ocular allergy signs and corneal biomechanical alterations.Methods: Thirty patients (30 eyes) with AC and twenty normal subjects (20 eyes) were included in this prospective study. All participants underwent a complete ocular examination, including corneal tomography by Pentacam and corneal biomechanics evaluation by Corvis ST. AC patients were evaluated for their eye rubbing frequency and ocular allergic signs.Results: The elevation at the thinnest location (TE) and the central location (CE), the elevation difference at the thinnest location (TED) and the central location (CED), and the mean value of elevation difference in the central 4 mm zoom (MED) of both the anterior and posterior corneal surface were significantly higher in the AC group than in the normal group (p < 0.05 for all). In AC patients, only anterior corneal elevation parameters were positively correlated with eye rubbing frequency and ocular allergy sign severity (p < 0.05 for all), while the tomography and biomechanical index (TBI) was positively correlated with the elevation parameters of both the anterior and posterior corneal surfaces (p < 0.05 for all).Conclusion: AC patients carry an increased risk of corneal ectasia. Posterior corneal elevation parameters are sensitive and reliable predictors of keratoconus (KC) risk in AC patients.Clinical Trial Registration:https://clinicaltrials.gov/ct2/show/NCT04299399, identifier [NCT04299399].
format	article
author	Qian Wang Fei Yu Ziqing Feng Weihua Li Naiyang Li Xinyue Du Xuan Zhao Saiqun Li Jin Yuan
author_facet	Qian Wang Fei Yu Ziqing Feng Weihua Li Naiyang Li Xinyue Du Xuan Zhao Saiqun Li Jin Yuan
author_sort	Qian Wang
title	Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis
title_short	Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis
title_full	Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis
title_fullStr	Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis
title_full_unstemmed	Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis
title_sort	changes in anterior and posterior corneal elevation in patients with allergic conjunctivitis
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/c6e53847f46349ac8031fc0558c3093e
work_keys_str_mv	AT qianwang changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT feiyu changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT ziqingfeng changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT weihuali changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT naiyangli changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT xinyuedu changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT xuanzhao changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT saiqunli changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis AT jinyuan changesinanteriorandposteriorcornealelevationinpatientswithallergicconjunctivitis
_version_	1718406470694862848

Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis

Ejemplares similares