The role of apoptosis in pathogenesis of type 1 diabetes mellitus
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes i...
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Main Authors: | Elena Vladimirovna Pekareva, Tatiana Vasil'evna Nikonova, Olga Mikhailovna Smirnova |
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Format: | article |
Language: | EN RU |
Published: |
Endocrinology Research Centre
2010
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Online Access: | https://doaj.org/article/c6ee29cf448846dab828aa2a84d58b98 |
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