Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography

Abstract This study aims to quantitatively investigate the optical coherence tomographic angiography (OCTA) findings of capillary congestion and its association with macular edema (ME) recurrence in chronic branch retinal vein occlusion (BRVO). We retrospectively reviewed the medical records of 115...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Min Seung Kang, Sang Yoon Kim, Sung Who Park, Ik Soo Byon, Han Jo Kwon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c6f30b20ad2f41c39ea268b3432eb4de
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c6f30b20ad2f41c39ea268b3432eb4de
record_format	dspace
spelling	oai:doaj.org-article:c6f30b20ad2f41c39ea268b3432eb4de2021-12-02T18:37:10ZAssociation between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography10.1038/s41598-021-99429-z2045-2322https://doaj.org/article/c6f30b20ad2f41c39ea268b3432eb4de2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-99429-zhttps://doaj.org/toc/2045-2322Abstract This study aims to quantitatively investigate the optical coherence tomographic angiography (OCTA) findings of capillary congestion and its association with macular edema (ME) recurrence in chronic branch retinal vein occlusion (BRVO). We retrospectively reviewed the medical records of 115 consecutive patients with major ischemic BRVO who reached stable macula (without ME for two consecutive visits) at baseline (the first visit within the stable period). All patients were classified into a recurrence or non-recurrence groups depending on ME recurrence. Capillary congestion of deep capillary plexuses (DCP-C) and other abnormal capillary lesions were segmented, and their areas, vascular densities, and mean retinal thicknesses (MRT) were calculated. The main outcomes were differences between the two groups and risk factors for recurrence among baseline and OCTA parameters. A total of 76 eyes were included, of which 22 (28.9%) recurred. DCP-C existed in all eyes at baseline. MRT of DCP-C (p = 0.006) was greater in the recurrence group. Greater MRT of DCP-C (OR: 1.044; p = 0.002) and more frequent intravitreal injections (OR: 1.803; p < 0.001) were associated with a higher risk of relapsing ME. DCP-C may contribute to the anatomical stability of chronic BRVO and simultaneously be the source of ME.Min Seung KangSang Yoon KimSung Who ParkIk Soo ByonHan Jo KwonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Min Seung Kang Sang Yoon Kim Sung Who Park Ik Soo Byon Han Jo Kwon Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography
description	Abstract This study aims to quantitatively investigate the optical coherence tomographic angiography (OCTA) findings of capillary congestion and its association with macular edema (ME) recurrence in chronic branch retinal vein occlusion (BRVO). We retrospectively reviewed the medical records of 115 consecutive patients with major ischemic BRVO who reached stable macula (without ME for two consecutive visits) at baseline (the first visit within the stable period). All patients were classified into a recurrence or non-recurrence groups depending on ME recurrence. Capillary congestion of deep capillary plexuses (DCP-C) and other abnormal capillary lesions were segmented, and their areas, vascular densities, and mean retinal thicknesses (MRT) were calculated. The main outcomes were differences between the two groups and risk factors for recurrence among baseline and OCTA parameters. A total of 76 eyes were included, of which 22 (28.9%) recurred. DCP-C existed in all eyes at baseline. MRT of DCP-C (p = 0.006) was greater in the recurrence group. Greater MRT of DCP-C (OR: 1.044; p = 0.002) and more frequent intravitreal injections (OR: 1.803; p < 0.001) were associated with a higher risk of relapsing ME. DCP-C may contribute to the anatomical stability of chronic BRVO and simultaneously be the source of ME.
format	article
author	Min Seung Kang Sang Yoon Kim Sung Who Park Ik Soo Byon Han Jo Kwon
author_facet	Min Seung Kang Sang Yoon Kim Sung Who Park Ik Soo Byon Han Jo Kwon
author_sort	Min Seung Kang
title	Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography
title_short	Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography
title_full	Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography
title_fullStr	Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography
title_full_unstemmed	Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography
title_sort	association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of oct angiography
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c6f30b20ad2f41c39ea268b3432eb4de
work_keys_str_mv	AT minseungkang associationbetweencapillarycongestionandmacularedemarecurrenceinchronicbranchretinalveinocclusionthroughquantitativeanalysisofoctangiography AT sangyoonkim associationbetweencapillarycongestionandmacularedemarecurrenceinchronicbranchretinalveinocclusionthroughquantitativeanalysisofoctangiography AT sungwhopark associationbetweencapillarycongestionandmacularedemarecurrenceinchronicbranchretinalveinocclusionthroughquantitativeanalysisofoctangiography AT iksoobyon associationbetweencapillarycongestionandmacularedemarecurrenceinchronicbranchretinalveinocclusionthroughquantitativeanalysisofoctangiography AT hanjokwon associationbetweencapillarycongestionandmacularedemarecurrenceinchronicbranchretinalveinocclusionthroughquantitativeanalysisofoctangiography
_version_	1718377825241661440

Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography

Ejemplares similares