Access to PCNA by Srs2 and Elg1 Controls the Choice between Alternative Repair Pathways in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>
ABSTRACT During DNA replication, stalling can occur when the replicative DNA polymerases encounter lesions or hard-to replicate regions. Under these circumstances, the processivity factor PCNA gets ubiquitylated at lysine 164, inducing the DNA damage tolerance (DDT) mechanisms that can bypass lesion...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/c6fb9d83f3524b178fcfaa153a1f91ba |
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