Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells

Astrocytes have been shown to regulate glutamatergic transmission in the brain. Here, the authors show that astrocytes also detect and modulate GABAergic transmission from somatostatin but not parvalbumin-positive interneurons, thus regulating dendritic inhibition via a feedback loop.

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Detalles Bibliográficos
Autores principales: Marco Matos, Anthony Bosson, Ilse Riebe, Clare Reynell, Joanne Vallée, Isabel Laplante, Aude Panatier, Richard Robitaille, Jean-Claude Lacaille
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c6fbd67d0f05474a95401584d80c4492
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Descripción
Sumario:Astrocytes have been shown to regulate glutamatergic transmission in the brain. Here, the authors show that astrocytes also detect and modulate GABAergic transmission from somatostatin but not parvalbumin-positive interneurons, thus regulating dendritic inhibition via a feedback loop.