Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells

Astrocytes have been shown to regulate glutamatergic transmission in the brain. Here, the authors show that astrocytes also detect and modulate GABAergic transmission from somatostatin but not parvalbumin-positive interneurons, thus regulating dendritic inhibition via a feedback loop.

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Autores principales:	Marco Matos, Anthony Bosson, Ilse Riebe, Clare Reynell, Joanne Vallée, Isabel Laplante, Aude Panatier, Richard Robitaille, Jean-Claude Lacaille
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c6fbd67d0f05474a95401584d80c4492
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spelling	oai:doaj.org-article:c6fbd67d0f05474a95401584d80c44922021-12-02T16:49:21ZAstrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells10.1038/s41467-018-06731-y2041-1723https://doaj.org/article/c6fbd67d0f05474a95401584d80c44922018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06731-yhttps://doaj.org/toc/2041-1723Astrocytes have been shown to regulate glutamatergic transmission in the brain. Here, the authors show that astrocytes also detect and modulate GABAergic transmission from somatostatin but not parvalbumin-positive interneurons, thus regulating dendritic inhibition via a feedback loop.Marco MatosAnthony BossonIlse RiebeClare ReynellJoanne ValléeIsabel LaplanteAude PanatierRichard RobitailleJean-Claude LacailleNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marco Matos Anthony Bosson Ilse Riebe Clare Reynell Joanne Vallée Isabel Laplante Aude Panatier Richard Robitaille Jean-Claude Lacaille Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
description	Astrocytes have been shown to regulate glutamatergic transmission in the brain. Here, the authors show that astrocytes also detect and modulate GABAergic transmission from somatostatin but not parvalbumin-positive interneurons, thus regulating dendritic inhibition via a feedback loop.
format	article
author	Marco Matos Anthony Bosson Ilse Riebe Clare Reynell Joanne Vallée Isabel Laplante Aude Panatier Richard Robitaille Jean-Claude Lacaille
author_facet	Marco Matos Anthony Bosson Ilse Riebe Clare Reynell Joanne Vallée Isabel Laplante Aude Panatier Richard Robitaille Jean-Claude Lacaille
author_sort	Marco Matos
title	Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
title_short	Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
title_full	Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
title_fullStr	Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
title_full_unstemmed	Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
title_sort	astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c6fbd67d0f05474a95401584d80c4492
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Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells

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