Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody.

Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody.

<h4>Background</h4>Fc-glycosylation of monoclonal antibodies (mAbs) has profound implications on the Fc-mediated effector functions. Alteration of this glycosylation may affect the efficiency of an antibody. However, difficulties in the production of mAbs with homogeneous N-glycosylation...

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Autores principales: Alexandra Castilho, Natasha Bohorova, Josephine Grass, Ognian Bohorov, Larry Zeitlin, Kevin Whaley, Friedrich Altmann, Herta Steinkellner
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/c6fd415b0f934f4bb541f430c2038645
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