Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis
Cardiovascular risks of cold exposure and the subsequent activation of the β3-AR pathway limit the application of beige fat thermogenesis for the treatment of obesity. Here, the authors show that optogenetics light-activated Ca2+ cycling in adipocytes triggers a fat-specific “cold-mimetic” thermogen...
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Main Authors: | Kazuki Tajima, Kenji Ikeda, Yuji Tanabe, Ella A. Thomson, Takeshi Yoneshiro, Yasuo Oguri, Marc D. Ferro, Ada S. Y. Poon, Shingo Kajimura |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Subjects: | |
Online Access: | https://doaj.org/article/c6fe438eef6244abb2103d07bbb951d4 |
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