Testicular endothelial cells are a critical population in the germline stem cell niche

Self-renewal of spermatogonial stem cells (SSC) is necessary for spermatogenesis and male fertility. Here the authors identify testicular endothelial cells (TECs) as a source of 5 key growth factors for self-renewal and expansion of human and mouse SSCs.

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Autores principales: Dong Ha Bhang, Bang-Jin Kim, Byung Gak Kim, Keri Schadler, Kwan-Hyuck Baek, Yong Hee Kim, Wayland Hsiao, Bi-Sen Ding, Shahin Rafii, Mitchell J. Weiss, Stella T. Chou, Thomas F. Kolon, Jill P. Ginsberg, Buom-Yong Ryu, Sandra Ryeom
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c701091a3ecf450096905ad9df679dde
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spelling oai:doaj.org-article:c701091a3ecf450096905ad9df679dde2021-12-02T17:32:33ZTesticular endothelial cells are a critical population in the germline stem cell niche10.1038/s41467-018-06881-z2041-1723https://doaj.org/article/c701091a3ecf450096905ad9df679dde2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06881-zhttps://doaj.org/toc/2041-1723Self-renewal of spermatogonial stem cells (SSC) is necessary for spermatogenesis and male fertility. Here the authors identify testicular endothelial cells (TECs) as a source of 5 key growth factors for self-renewal and expansion of human and mouse SSCs.Dong Ha BhangBang-Jin KimByung Gak KimKeri SchadlerKwan-Hyuck BaekYong Hee KimWayland HsiaoBi-Sen DingShahin RafiiMitchell J. WeissStella T. ChouThomas F. KolonJill P. GinsbergBuom-Yong RyuSandra RyeomNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dong Ha Bhang
Bang-Jin Kim
Byung Gak Kim
Keri Schadler
Kwan-Hyuck Baek
Yong Hee Kim
Wayland Hsiao
Bi-Sen Ding
Shahin Rafii
Mitchell J. Weiss
Stella T. Chou
Thomas F. Kolon
Jill P. Ginsberg
Buom-Yong Ryu
Sandra Ryeom
Testicular endothelial cells are a critical population in the germline stem cell niche
description Self-renewal of spermatogonial stem cells (SSC) is necessary for spermatogenesis and male fertility. Here the authors identify testicular endothelial cells (TECs) as a source of 5 key growth factors for self-renewal and expansion of human and mouse SSCs.
format article
author Dong Ha Bhang
Bang-Jin Kim
Byung Gak Kim
Keri Schadler
Kwan-Hyuck Baek
Yong Hee Kim
Wayland Hsiao
Bi-Sen Ding
Shahin Rafii
Mitchell J. Weiss
Stella T. Chou
Thomas F. Kolon
Jill P. Ginsberg
Buom-Yong Ryu
Sandra Ryeom
author_facet Dong Ha Bhang
Bang-Jin Kim
Byung Gak Kim
Keri Schadler
Kwan-Hyuck Baek
Yong Hee Kim
Wayland Hsiao
Bi-Sen Ding
Shahin Rafii
Mitchell J. Weiss
Stella T. Chou
Thomas F. Kolon
Jill P. Ginsberg
Buom-Yong Ryu
Sandra Ryeom
author_sort Dong Ha Bhang
title Testicular endothelial cells are a critical population in the germline stem cell niche
title_short Testicular endothelial cells are a critical population in the germline stem cell niche
title_full Testicular endothelial cells are a critical population in the germline stem cell niche
title_fullStr Testicular endothelial cells are a critical population in the germline stem cell niche
title_full_unstemmed Testicular endothelial cells are a critical population in the germline stem cell niche
title_sort testicular endothelial cells are a critical population in the germline stem cell niche
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c701091a3ecf450096905ad9df679dde
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