Testicular endothelial cells are a critical population in the germline stem cell niche
Self-renewal of spermatogonial stem cells (SSC) is necessary for spermatogenesis and male fertility. Here the authors identify testicular endothelial cells (TECs) as a source of 5 key growth factors for self-renewal and expansion of human and mouse SSCs.
Guardado en:
Autores principales: | Dong Ha Bhang, Bang-Jin Kim, Byung Gak Kim, Keri Schadler, Kwan-Hyuck Baek, Yong Hee Kim, Wayland Hsiao, Bi-Sen Ding, Shahin Rafii, Mitchell J. Weiss, Stella T. Chou, Thomas F. Kolon, Jill P. Ginsberg, Buom-Yong Ryu, Sandra Ryeom |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c701091a3ecf450096905ad9df679dde |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Loss of putzig in the germline impedes germ cell development by inducing cell death and new niche like microenvironments
por: Ludmilla Kober, et al.
Publicado: (2019) -
Aging, inflammation and DNA damage in the somatic testicular niche with idiopathic germ cell aplasia
por: Massimo Alfano, et al.
Publicado: (2021) -
Efficient gene transfer into zebra finch germline-competent stem cells using an adenoviral vector system
por: Kyung Min Jung, et al.
Publicado: (2021) -
Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
por: Kun-Yang Lin, et al.
Publicado: (2020) -
Interspecific germline transmission of cultured primordial germ cells.
por: Marie-Cecile van de Lavoir, et al.
Publicado: (2012)