The Absence of (p)ppGpp Renders Initiation of <named-content content-type="genus-species">Escherichia coli</named-content> Chromosomal DNA Synthesis Independent of Growth Rates

The Absence of (p)ppGpp Renders Initiation of <named-content content-type="genus-species">Escherichia coli</named-content> Chromosomal DNA Synthesis Independent of Growth Rates

ABSTRACT The initiation of Escherichia coli chromosomal DNA replication starts with the oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The amount of ori DNA per cell directly correlates with the growth rate. During fast growth, the cell generation time is sho...

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Autores principales: Llorenç Fernández-Coll, Monika Maciag-Dorszynska, Krishma Tailor, Stephen Vadia, Petra Anne Levin, Agnieszka Szalewska-Palasz, Michael Cashel
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
chromosome initiation
DNA replication
Escherichia coli
growth rate
ppGpp
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/c70362e54d2e42d18cd060baed7d9443
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