Midbrain circuit regulation of individual alcohol drinking behaviors in mice
Mice exposed to a two-bottle alcohol choice paradigm can be divided into high and low drinking groups. Here, the authors show that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppresses alcohol drinking in mice that are high alcoh...
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c7189739a90a4202b1484c7c8679ab16 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:c7189739a90a4202b1484c7c8679ab16 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:c7189739a90a4202b1484c7c8679ab162021-12-02T17:06:03ZMidbrain circuit regulation of individual alcohol drinking behaviors in mice10.1038/s41467-017-02365-82041-1723https://doaj.org/article/c7189739a90a4202b1484c7c8679ab162017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02365-8https://doaj.org/toc/2041-1723Mice exposed to a two-bottle alcohol choice paradigm can be divided into high and low drinking groups. Here, the authors show that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppresses alcohol drinking in mice that are high alcohol drinking.Barbara JuarezCarole MorelStacy M. KuYutong LiuHongxing ZhangSarah MontgomeryHilledna GregoireEfrain RibeiroMarshall CrumillerCiorana Roman-OrtizJessica J. WalshKelcy JacksonDenise E. CrooteYingbo ZhuSong ZhangLeandro F. VendruscoloScott EdwardsAmanda RobertsGeorgia E. HodesYongke LuErin S. CalipariDipesh ChaudhuryAllyson K. FriedmanMing-Hu HanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Barbara Juarez Carole Morel Stacy M. Ku Yutong Liu Hongxing Zhang Sarah Montgomery Hilledna Gregoire Efrain Ribeiro Marshall Crumiller Ciorana Roman-Ortiz Jessica J. Walsh Kelcy Jackson Denise E. Croote Yingbo Zhu Song Zhang Leandro F. Vendruscolo Scott Edwards Amanda Roberts Georgia E. Hodes Yongke Lu Erin S. Calipari Dipesh Chaudhury Allyson K. Friedman Ming-Hu Han Midbrain circuit regulation of individual alcohol drinking behaviors in mice |
description |
Mice exposed to a two-bottle alcohol choice paradigm can be divided into high and low drinking groups. Here, the authors show that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppresses alcohol drinking in mice that are high alcohol drinking. |
format |
article |
author |
Barbara Juarez Carole Morel Stacy M. Ku Yutong Liu Hongxing Zhang Sarah Montgomery Hilledna Gregoire Efrain Ribeiro Marshall Crumiller Ciorana Roman-Ortiz Jessica J. Walsh Kelcy Jackson Denise E. Croote Yingbo Zhu Song Zhang Leandro F. Vendruscolo Scott Edwards Amanda Roberts Georgia E. Hodes Yongke Lu Erin S. Calipari Dipesh Chaudhury Allyson K. Friedman Ming-Hu Han |
author_facet |
Barbara Juarez Carole Morel Stacy M. Ku Yutong Liu Hongxing Zhang Sarah Montgomery Hilledna Gregoire Efrain Ribeiro Marshall Crumiller Ciorana Roman-Ortiz Jessica J. Walsh Kelcy Jackson Denise E. Croote Yingbo Zhu Song Zhang Leandro F. Vendruscolo Scott Edwards Amanda Roberts Georgia E. Hodes Yongke Lu Erin S. Calipari Dipesh Chaudhury Allyson K. Friedman Ming-Hu Han |
author_sort |
Barbara Juarez |
title |
Midbrain circuit regulation of individual alcohol drinking behaviors in mice |
title_short |
Midbrain circuit regulation of individual alcohol drinking behaviors in mice |
title_full |
Midbrain circuit regulation of individual alcohol drinking behaviors in mice |
title_fullStr |
Midbrain circuit regulation of individual alcohol drinking behaviors in mice |
title_full_unstemmed |
Midbrain circuit regulation of individual alcohol drinking behaviors in mice |
title_sort |
midbrain circuit regulation of individual alcohol drinking behaviors in mice |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c7189739a90a4202b1484c7c8679ab16 |
work_keys_str_mv |
AT barbarajuarez midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT carolemorel midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT stacymku midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT yutongliu midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT hongxingzhang midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT sarahmontgomery midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT hillednagregoire midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT efrainribeiro midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT marshallcrumiller midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT cioranaromanortiz midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT jessicajwalsh midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT kelcyjackson midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT deniseecroote midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT yingbozhu midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT songzhang midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT leandrofvendruscolo midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT scottedwards midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT amandaroberts midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT georgiaehodes midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT yongkelu midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT erinscalipari midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT dipeshchaudhury midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT allysonkfriedman midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice AT minghuhan midbraincircuitregulationofindividualalcoholdrinkingbehaviorsinmice |
_version_ |
1718381755813068800 |