Midbrain circuit regulation of individual alcohol drinking behaviors in mice

Mice exposed to a two-bottle alcohol choice paradigm can be divided into high and low drinking groups. Here, the authors show that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppresses alcohol drinking in mice that are high alcoh...

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Autores principales: Barbara Juarez, Carole Morel, Stacy M. Ku, Yutong Liu, Hongxing Zhang, Sarah Montgomery, Hilledna Gregoire, Efrain Ribeiro, Marshall Crumiller, Ciorana Roman-Ortiz, Jessica J. Walsh, Kelcy Jackson, Denise E. Croote, Yingbo Zhu, Song Zhang, Leandro F. Vendruscolo, Scott Edwards, Amanda Roberts, Georgia E. Hodes, Yongke Lu, Erin S. Calipari, Dipesh Chaudhury, Allyson K. Friedman, Ming-Hu Han
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c7189739a90a4202b1484c7c8679ab16
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spelling oai:doaj.org-article:c7189739a90a4202b1484c7c8679ab162021-12-02T17:06:03ZMidbrain circuit regulation of individual alcohol drinking behaviors in mice10.1038/s41467-017-02365-82041-1723https://doaj.org/article/c7189739a90a4202b1484c7c8679ab162017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02365-8https://doaj.org/toc/2041-1723Mice exposed to a two-bottle alcohol choice paradigm can be divided into high and low drinking groups. Here, the authors show that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppresses alcohol drinking in mice that are high alcohol drinking.Barbara JuarezCarole MorelStacy M. KuYutong LiuHongxing ZhangSarah MontgomeryHilledna GregoireEfrain RibeiroMarshall CrumillerCiorana Roman-OrtizJessica J. WalshKelcy JacksonDenise E. CrooteYingbo ZhuSong ZhangLeandro F. VendruscoloScott EdwardsAmanda RobertsGeorgia E. HodesYongke LuErin S. CalipariDipesh ChaudhuryAllyson K. FriedmanMing-Hu HanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Barbara Juarez
Carole Morel
Stacy M. Ku
Yutong Liu
Hongxing Zhang
Sarah Montgomery
Hilledna Gregoire
Efrain Ribeiro
Marshall Crumiller
Ciorana Roman-Ortiz
Jessica J. Walsh
Kelcy Jackson
Denise E. Croote
Yingbo Zhu
Song Zhang
Leandro F. Vendruscolo
Scott Edwards
Amanda Roberts
Georgia E. Hodes
Yongke Lu
Erin S. Calipari
Dipesh Chaudhury
Allyson K. Friedman
Ming-Hu Han
Midbrain circuit regulation of individual alcohol drinking behaviors in mice
description Mice exposed to a two-bottle alcohol choice paradigm can be divided into high and low drinking groups. Here, the authors show that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppresses alcohol drinking in mice that are high alcohol drinking.
format article
author Barbara Juarez
Carole Morel
Stacy M. Ku
Yutong Liu
Hongxing Zhang
Sarah Montgomery
Hilledna Gregoire
Efrain Ribeiro
Marshall Crumiller
Ciorana Roman-Ortiz
Jessica J. Walsh
Kelcy Jackson
Denise E. Croote
Yingbo Zhu
Song Zhang
Leandro F. Vendruscolo
Scott Edwards
Amanda Roberts
Georgia E. Hodes
Yongke Lu
Erin S. Calipari
Dipesh Chaudhury
Allyson K. Friedman
Ming-Hu Han
author_facet Barbara Juarez
Carole Morel
Stacy M. Ku
Yutong Liu
Hongxing Zhang
Sarah Montgomery
Hilledna Gregoire
Efrain Ribeiro
Marshall Crumiller
Ciorana Roman-Ortiz
Jessica J. Walsh
Kelcy Jackson
Denise E. Croote
Yingbo Zhu
Song Zhang
Leandro F. Vendruscolo
Scott Edwards
Amanda Roberts
Georgia E. Hodes
Yongke Lu
Erin S. Calipari
Dipesh Chaudhury
Allyson K. Friedman
Ming-Hu Han
author_sort Barbara Juarez
title Midbrain circuit regulation of individual alcohol drinking behaviors in mice
title_short Midbrain circuit regulation of individual alcohol drinking behaviors in mice
title_full Midbrain circuit regulation of individual alcohol drinking behaviors in mice
title_fullStr Midbrain circuit regulation of individual alcohol drinking behaviors in mice
title_full_unstemmed Midbrain circuit regulation of individual alcohol drinking behaviors in mice
title_sort midbrain circuit regulation of individual alcohol drinking behaviors in mice
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c7189739a90a4202b1484c7c8679ab16
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