The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience

In this work we intend to validate the long-term oncologic outcomes for very low rectal cancer over the past 20 years and to determine whether laparoscopic procedures are useful options for very low rectal cancer. A total of 327 patients, who electively underwent laparoscopic rectal cancer surgery f...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hyuk-Jun Chung, Jun-Gi Kim, Hyung-Jin Kim, Hyeon-Min Cho, Bong-Hyeon Kye
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	very low rectal cancer sphincter saving surgery laparoscopic surgery oncologic outcomes Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c720d38b40a84e84a44d9bdc7e4baab0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c720d38b40a84e84a44d9bdc7e4baab0
record_format	dspace
spelling	oai:doaj.org-article:c720d38b40a84e84a44d9bdc7e4baab02021-11-25T16:51:22ZThe Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience10.3390/biomedicines91117202227-9059https://doaj.org/article/c720d38b40a84e84a44d9bdc7e4baab02021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9059/9/11/1720https://doaj.org/toc/2227-9059In this work we intend to validate the long-term oncologic outcomes for very low rectal cancer over the past 20 years and to determine whether laparoscopic procedures are useful options for very low rectal cancer. A total of 327 patients, who electively underwent laparoscopic rectal cancer surgery for a lesion within 5 cm from the anal verge, were enrolled in this study and their long-term outcomes were reviewed retrospectively. Of 327 patients, 70 patients underwent laparoscopic low anterior resection (LAR), 164 underwent laparoscopic abdominal transanal proctosigmoidocolectomy with coloanal anastomosis (LATA), and 93 underwent laparoscopic abdominoperineal resection (APR). The conversion rate was 1.22% (4/327). The overall postoperative morbidity rate was 26.30% (86/327). The 5-year disease free survival (DFS), 5-year overall survival (OS), and 3-year local recurrence (LR) were 64.3%, 79.7%, and 9.2%, respectively. The CRM involvement was a significant independent factor for DFS (<i>p</i> = 0.018) and OS (<i>p</i> = 0.042) in multivariate analysis. Laparoscopic APR showed poorer 5-year DFS (47.8%), 5-year OS (64.0%), and 3-year LR (17.6%) than laparoscopic LAR (74.1%, 86.4%, 1.9%) and laparoscopic LATA (69.2%, 83.6%, 9.2%). Laparoscopic procedures for very low rectal cancer including LAR, LATA, and APR could be good surgical options in selective patients with very low rectal cancer.Hyuk-Jun ChungJun-Gi KimHyung-Jin KimHyeon-Min ChoBong-Hyeon KyeMDPI AGarticlevery low rectal cancersphincter saving surgerylaparoscopic surgeryoncologic outcomesBiology (General)QH301-705.5ENBiomedicines, Vol 9, Iss 1720, p 1720 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	very low rectal cancer sphincter saving surgery laparoscopic surgery oncologic outcomes Biology (General) QH301-705.5
spellingShingle	very low rectal cancer sphincter saving surgery laparoscopic surgery oncologic outcomes Biology (General) QH301-705.5 Hyuk-Jun Chung Jun-Gi Kim Hyung-Jin Kim Hyeon-Min Cho Bong-Hyeon Kye The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
description	In this work we intend to validate the long-term oncologic outcomes for very low rectal cancer over the past 20 years and to determine whether laparoscopic procedures are useful options for very low rectal cancer. A total of 327 patients, who electively underwent laparoscopic rectal cancer surgery for a lesion within 5 cm from the anal verge, were enrolled in this study and their long-term outcomes were reviewed retrospectively. Of 327 patients, 70 patients underwent laparoscopic low anterior resection (LAR), 164 underwent laparoscopic abdominal transanal proctosigmoidocolectomy with coloanal anastomosis (LATA), and 93 underwent laparoscopic abdominoperineal resection (APR). The conversion rate was 1.22% (4/327). The overall postoperative morbidity rate was 26.30% (86/327). The 5-year disease free survival (DFS), 5-year overall survival (OS), and 3-year local recurrence (LR) were 64.3%, 79.7%, and 9.2%, respectively. The CRM involvement was a significant independent factor for DFS (<i>p</i> = 0.018) and OS (<i>p</i> = 0.042) in multivariate analysis. Laparoscopic APR showed poorer 5-year DFS (47.8%), 5-year OS (64.0%), and 3-year LR (17.6%) than laparoscopic LAR (74.1%, 86.4%, 1.9%) and laparoscopic LATA (69.2%, 83.6%, 9.2%). Laparoscopic procedures for very low rectal cancer including LAR, LATA, and APR could be good surgical options in selective patients with very low rectal cancer.
format	article
author	Hyuk-Jun Chung Jun-Gi Kim Hyung-Jin Kim Hyeon-Min Cho Bong-Hyeon Kye
author_facet	Hyuk-Jun Chung Jun-Gi Kim Hyung-Jin Kim Hyeon-Min Cho Bong-Hyeon Kye
author_sort	Hyuk-Jun Chung
title	The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
title_short	The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
title_full	The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
title_fullStr	The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
title_full_unstemmed	The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
title_sort	safety and feasibility of laparoscopic surgery for very low rectal cancer: a retrospective analysis based on a single center’s experience
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c720d38b40a84e84a44d9bdc7e4baab0
work_keys_str_mv	AT hyukjunchung thesafetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT jungikim thesafetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT hyungjinkim thesafetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT hyeonmincho thesafetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT bonghyeonkye thesafetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT hyukjunchung safetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT jungikim safetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT hyungjinkim safetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT hyeonmincho safetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience AT bonghyeonkye safetyandfeasibilityoflaparoscopicsurgeryforverylowrectalcanceraretrospectiveanalysisbasedonasinglecentersexperience
_version_	1718412922111131648

The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience

Ejemplares similares