Quantifying compressive forces between living cell layers and within tissues using elastic round microgels

Increasing importance is placed upon the effect of mechanical forces on cell regulation, fate and disease states. Here, the authors describe a deformable fluorescent nanoparticle labeled elastic microsphere which can be used to calculate strain and traction forces in vitro and in vivo.

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Autores principales: Erfan Mohagheghian, Junyu Luo, Junjian Chen, Gaurav Chaudhary, Junwei Chen, Jian Sun, Randy H. Ewoldt, Ning Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c72b3aa206494ddc9840377829e15d7e
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spelling oai:doaj.org-article:c72b3aa206494ddc9840377829e15d7e2021-12-02T16:56:59ZQuantifying compressive forces between living cell layers and within tissues using elastic round microgels10.1038/s41467-018-04245-12041-1723https://doaj.org/article/c72b3aa206494ddc9840377829e15d7e2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04245-1https://doaj.org/toc/2041-1723Increasing importance is placed upon the effect of mechanical forces on cell regulation, fate and disease states. Here, the authors describe a deformable fluorescent nanoparticle labeled elastic microsphere which can be used to calculate strain and traction forces in vitro and in vivo.Erfan MohagheghianJunyu LuoJunjian ChenGaurav ChaudharyJunwei ChenJian SunRandy H. EwoldtNing WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Erfan Mohagheghian
Junyu Luo
Junjian Chen
Gaurav Chaudhary
Junwei Chen
Jian Sun
Randy H. Ewoldt
Ning Wang
Quantifying compressive forces between living cell layers and within tissues using elastic round microgels
description Increasing importance is placed upon the effect of mechanical forces on cell regulation, fate and disease states. Here, the authors describe a deformable fluorescent nanoparticle labeled elastic microsphere which can be used to calculate strain and traction forces in vitro and in vivo.
format article
author Erfan Mohagheghian
Junyu Luo
Junjian Chen
Gaurav Chaudhary
Junwei Chen
Jian Sun
Randy H. Ewoldt
Ning Wang
author_facet Erfan Mohagheghian
Junyu Luo
Junjian Chen
Gaurav Chaudhary
Junwei Chen
Jian Sun
Randy H. Ewoldt
Ning Wang
author_sort Erfan Mohagheghian
title Quantifying compressive forces between living cell layers and within tissues using elastic round microgels
title_short Quantifying compressive forces between living cell layers and within tissues using elastic round microgels
title_full Quantifying compressive forces between living cell layers and within tissues using elastic round microgels
title_fullStr Quantifying compressive forces between living cell layers and within tissues using elastic round microgels
title_full_unstemmed Quantifying compressive forces between living cell layers and within tissues using elastic round microgels
title_sort quantifying compressive forces between living cell layers and within tissues using elastic round microgels
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c72b3aa206494ddc9840377829e15d7e
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