Development of an in vitro measurement method for improved assessment of the side branch expansion capacity

The expansion capacity and accessibility of the side branch is essential for the stenting of complex bifurcations. Since previous measurement methods only provide limited information based on geometrical data of stent cells, a new measurement approach was developed which considers the mechanical def...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rosam Paula, Borowski Finja, Stiehm Michael, Schmitz Klaus Peter, Keiler Jonas, Wree Andreas, Öner Alper Ö, Schmidt Wolfram
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2020
Materias:
R
Acceso en línea:https://doaj.org/article/c732a82843944a548da9bf74ecc3730e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:c732a82843944a548da9bf74ecc3730e
record_format dspace
spelling oai:doaj.org-article:c732a82843944a548da9bf74ecc3730e2021-12-05T14:10:43ZDevelopment of an in vitro measurement method for improved assessment of the side branch expansion capacity2364-550410.1515/cdbme-2020-3114https://doaj.org/article/c732a82843944a548da9bf74ecc3730e2020-09-01T00:00:00Zhttps://doi.org/10.1515/cdbme-2020-3114https://doaj.org/toc/2364-5504The expansion capacity and accessibility of the side branch is essential for the stenting of complex bifurcations. Since previous measurement methods only provide limited information based on geometrical data of stent cells, a new measurement approach was developed which considers the mechanical deformation capacity of the stent design. This approach provides essential information on the stent with regard to the application of bifurcation stenting. Four different commercially available coronary stents (nominal diameter 3.0 mm) were dilated and a central strut cell was over-expanded by means balloon catheters of increasing nominal diameter (2.0 to 5.0 mm). After balloon inflation, the remaining cell size was investigated for maximum cell diameter and strut fractures. Large expansion capacity without cell damage is taken as a measure of the accessibility of the side branch. In none of the expansion experiments the desired target size could be achieved, which is due to the elastic recoil of the stent cells. Deviations from the target diameter between 14-38% were determined. However, larger diameters also showed a constriction of the balloon, so that in some cases the target diameter could not be achieved at all. No strut fractures occurred even at maximum balloon diameter and pressure (5.0 mm noncompliant balloons). As a result the side branch accessibility differs depending on the individual stent designs. No particular risk for the stent was found by extensive overdilatation.Rosam PaulaBorowski FinjaStiehm MichaelSchmitz Klaus PeterKeiler JonasWree AndreasÖner Alper ÖSchmidt WolframDe Gruyterarticlestentsside branch accessibilityexpansion capacitystrut deformationbifurcationMedicineRENCurrent Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 442-445 (2020)
institution DOAJ
collection DOAJ
language EN
topic stents
side branch accessibility
expansion capacity
strut deformation
bifurcation
Medicine
R
spellingShingle stents
side branch accessibility
expansion capacity
strut deformation
bifurcation
Medicine
R
Rosam Paula
Borowski Finja
Stiehm Michael
Schmitz Klaus Peter
Keiler Jonas
Wree Andreas
Öner Alper Ö
Schmidt Wolfram
Development of an in vitro measurement method for improved assessment of the side branch expansion capacity
description The expansion capacity and accessibility of the side branch is essential for the stenting of complex bifurcations. Since previous measurement methods only provide limited information based on geometrical data of stent cells, a new measurement approach was developed which considers the mechanical deformation capacity of the stent design. This approach provides essential information on the stent with regard to the application of bifurcation stenting. Four different commercially available coronary stents (nominal diameter 3.0 mm) were dilated and a central strut cell was over-expanded by means balloon catheters of increasing nominal diameter (2.0 to 5.0 mm). After balloon inflation, the remaining cell size was investigated for maximum cell diameter and strut fractures. Large expansion capacity without cell damage is taken as a measure of the accessibility of the side branch. In none of the expansion experiments the desired target size could be achieved, which is due to the elastic recoil of the stent cells. Deviations from the target diameter between 14-38% were determined. However, larger diameters also showed a constriction of the balloon, so that in some cases the target diameter could not be achieved at all. No strut fractures occurred even at maximum balloon diameter and pressure (5.0 mm noncompliant balloons). As a result the side branch accessibility differs depending on the individual stent designs. No particular risk for the stent was found by extensive overdilatation.
format article
author Rosam Paula
Borowski Finja
Stiehm Michael
Schmitz Klaus Peter
Keiler Jonas
Wree Andreas
Öner Alper Ö
Schmidt Wolfram
author_facet Rosam Paula
Borowski Finja
Stiehm Michael
Schmitz Klaus Peter
Keiler Jonas
Wree Andreas
Öner Alper Ö
Schmidt Wolfram
author_sort Rosam Paula
title Development of an in vitro measurement method for improved assessment of the side branch expansion capacity
title_short Development of an in vitro measurement method for improved assessment of the side branch expansion capacity
title_full Development of an in vitro measurement method for improved assessment of the side branch expansion capacity
title_fullStr Development of an in vitro measurement method for improved assessment of the side branch expansion capacity
title_full_unstemmed Development of an in vitro measurement method for improved assessment of the side branch expansion capacity
title_sort development of an in vitro measurement method for improved assessment of the side branch expansion capacity
publisher De Gruyter
publishDate 2020
url https://doaj.org/article/c732a82843944a548da9bf74ecc3730e
work_keys_str_mv AT rosampaula developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
AT borowskifinja developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
AT stiehmmichael developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
AT schmitzklauspeter developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
AT keilerjonas developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
AT wreeandreas developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
AT oneralpero developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
AT schmidtwolfram developmentofaninvitromeasurementmethodforimprovedassessmentofthesidebranchexpansioncapacity
_version_ 1718371807707267072