Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites
Meng-Hsuan Lin et al. investigate MERS-CoV macro domain binding selectivity with NAD and NAD metabolites under various conditions. At physiological temperature, NAD is observed to have enhanced binding affinity to the MERS-CoV macro domain, shedding light on a new possible role of the MERS-CoV macro...
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Main Authors: | Meng-Hsuan Lin, Chao-Cheng Cho, Yi-Chih Chiu, Chia-Yu Chien, Yi-Ping Huang, Chi-Fon Chang, Chun-Hua Hsu |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/c746f4f54dab40188dea1673f5a05a7b |
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