EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors.

EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors.

<h4>Background</h4>Gain-of-function of erythropoietin receptor (EPOR) mutations represent the major cause of primary hereditary polycythemia. EPOR is also found in non-erythroid tissues, although its physiological role is still undefined.<h4>Methodology/principal findings</h4>...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Silverio Perrotta, Valeria Cucciolla, Marcella Ferraro, Luisa Ronzoni, Annunziata Tramontano, Francesca Rossi, Anna Chiara Scudieri, Adriana Borriello, Domenico Roberti, Bruno Nobili, Maria Domenica Cappellini, Adriana Oliva, Giovanni Amendola, Anna Rita Migliaccio, Patrizia Mancuso, Ines Martin-Padura, Francesco Bertolini, Donghoon Yoon, Josef T Prchal, Fulvio Della Ragione
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/c749460bfd1e4e51998c1c626fd9cba6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares