Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice

How hair follicle regeneration arises readily in some species ie. spiny rather than laboratory mice, is unclear. Here, authors compare them, showing an optimal stiffness is needed for placode formation and the difference in hair follicle regenerative behaviour after wounding is linked to Twist1.

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Autores principales: Hans I-Chen Harn, Sheng-Pei Wang, Yung-Chih Lai, Ben Van Handel, Ya-Chen Liang, Stephanie Tsai, Ina Maria Schiessl, Arijita Sarkar, Haibin Xi, Michael Hughes, Stefan Kaemmer, Ming-Jer Tang, Janos Peti-Peterdi, April D. Pyle, Thomas E. Woolley, Denis Evseenko, Ting-Xin Jiang, Cheng-Ming Chuong
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c7529f01880d4450966fe241daf10441
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spelling oai:doaj.org-article:c7529f01880d4450966fe241daf104412021-12-02T15:36:28ZSymmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice10.1038/s41467-021-22822-92041-1723https://doaj.org/article/c7529f01880d4450966fe241daf104412021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22822-9https://doaj.org/toc/2041-1723How hair follicle regeneration arises readily in some species ie. spiny rather than laboratory mice, is unclear. Here, authors compare them, showing an optimal stiffness is needed for placode formation and the difference in hair follicle regenerative behaviour after wounding is linked to Twist1.Hans I-Chen HarnSheng-Pei WangYung-Chih LaiBen Van HandelYa-Chen LiangStephanie TsaiIna Maria SchiesslArijita SarkarHaibin XiMichael HughesStefan KaemmerMing-Jer TangJanos Peti-PeterdiApril D. PyleThomas E. WoolleyDenis EvseenkoTing-Xin JiangCheng-Ming ChuongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hans I-Chen Harn
Sheng-Pei Wang
Yung-Chih Lai
Ben Van Handel
Ya-Chen Liang
Stephanie Tsai
Ina Maria Schiessl
Arijita Sarkar
Haibin Xi
Michael Hughes
Stefan Kaemmer
Ming-Jer Tang
Janos Peti-Peterdi
April D. Pyle
Thomas E. Woolley
Denis Evseenko
Ting-Xin Jiang
Cheng-Ming Chuong
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
description How hair follicle regeneration arises readily in some species ie. spiny rather than laboratory mice, is unclear. Here, authors compare them, showing an optimal stiffness is needed for placode formation and the difference in hair follicle regenerative behaviour after wounding is linked to Twist1.
format article
author Hans I-Chen Harn
Sheng-Pei Wang
Yung-Chih Lai
Ben Van Handel
Ya-Chen Liang
Stephanie Tsai
Ina Maria Schiessl
Arijita Sarkar
Haibin Xi
Michael Hughes
Stefan Kaemmer
Ming-Jer Tang
Janos Peti-Peterdi
April D. Pyle
Thomas E. Woolley
Denis Evseenko
Ting-Xin Jiang
Cheng-Ming Chuong
author_facet Hans I-Chen Harn
Sheng-Pei Wang
Yung-Chih Lai
Ben Van Handel
Ya-Chen Liang
Stephanie Tsai
Ina Maria Schiessl
Arijita Sarkar
Haibin Xi
Michael Hughes
Stefan Kaemmer
Ming-Jer Tang
Janos Peti-Peterdi
April D. Pyle
Thomas E. Woolley
Denis Evseenko
Ting-Xin Jiang
Cheng-Ming Chuong
author_sort Hans I-Chen Harn
title Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
title_short Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
title_full Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
title_fullStr Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
title_full_unstemmed Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
title_sort symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c7529f01880d4450966fe241daf10441
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