Neurofilament Levels Are Reflecting the Loss of Presynaptic Dopamine Receptors in Movement Disorders

Neurofilament Levels Are Reflecting the Loss of Presynaptic Dopamine Receptors in Movement Disorders

Aims: Neurofilament light chain (NfL) and phosphorylated neurofilament heavy chain (pNfH) are biomarkers for neuroaxonal damage. We assessed whether NfL and other biomarker levels in the CSF are correlated to the loss of presynaptic dopamine transporters in neurons as detected with dopamine transpor...

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Autores principales: Elena Diekämper, Britta Brix, Winfried Stöcker, Stefan Vielhaber, Imke Galazky, Michael C. Kreissl, Philipp Genseke, Emrah Düzel, Péter Körtvelyessy
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
neurofilament light chain
movement disorders
DaTscan
Parkinson’s Disease
CSF
alpha-synuclein
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Acceso en línea:https://doaj.org/article/c75d63963c094a3a86857a4e74a006a6
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https://doaj.org/article/c75d63963c094a3a86857a4e74a006a6

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