Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study

Abstract We evaluated the 6-year incidence and risk factors of pterygium in a multi-ethnic Asian population. Participants who attended the baseline visit of the Singapore Epidemiology of Eye Diseases Study (year 2004–2011) and returned six years later, were included in this study. Pterygium was diag...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xiao Ling Fang, Crystal Chun Yuen Chong, Sahil Thakur, Zhi Da Soh, Zhen Ling Teo, Shivani Majithia, Zhi Wei Lim, Tyler Hyungtaek Rim, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Yih-Chung Tham
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c769e01d4b9b46cb9a5a928b96145b71
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c769e01d4b9b46cb9a5a928b96145b71
record_format	dspace
spelling	oai:doaj.org-article:c769e01d4b9b46cb9a5a928b96145b712021-12-02T15:23:02ZEthnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study10.1038/s41598-020-79920-92045-2322https://doaj.org/article/c769e01d4b9b46cb9a5a928b96145b712021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-79920-9https://doaj.org/toc/2045-2322Abstract We evaluated the 6-year incidence and risk factors of pterygium in a multi-ethnic Asian population. Participants who attended the baseline visit of the Singapore Epidemiology of Eye Diseases Study (year 2004–2011) and returned six years later, were included in this study. Pterygium was diagnosed based on anterior segment photographs. Incident pterygium was defined as presence of pterygium at 6-year follow-up in either eye, among individuals without pterygium at baseline. Multivariable logistic regression models were used to determine factors associated with incident pterygium, adjusting for baseline age, gender, ethnicity, body mass index, occupation type, educational level, income status, smoking, alcohol consumption, presence of hypertension, diabetes and hyperlipidemia. The overall age-adjusted 6-year incidence of pterygium was 1.2% (95% confidence interval [CI] 1.0–1.6%); with Chinese (1.9%; 95% CI 1.4%-2.5%) having the highest incidence rate followed by Malays (1.4%; 95% CI 0.9%-2.1%) and Indians (0.3%; 95% CI 0.3–0.7%). In multivariable analysis, Chinese (compared with Indians; odds ratio [OR] = 4.21; 95% CI 2.12–9.35) and Malays (OR 3.22; 95% CI 1.52–7.45), male (OR 2.13; 95% CI 1.26–3.63), outdoor occupation (OR 2.33; 95% CI 1.16–4.38), and smoking (OR 0.41; 95% CI 0.16–0.87) were significantly associated with incident pterygium. Findings from this multi-ethnic Asian population provide useful information in identifying at-risk individuals for pterygium.Xiao Ling FangCrystal Chun Yuen ChongSahil ThakurZhi Da SohZhen Ling TeoShivani MajithiaZhi Wei LimTyler Hyungtaek RimCharumathi SabanayagamTien Yin WongChing-Yu ChengYih-Chung ThamNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xiao Ling Fang Crystal Chun Yuen Chong Sahil Thakur Zhi Da Soh Zhen Ling Teo Shivani Majithia Zhi Wei Lim Tyler Hyungtaek Rim Charumathi Sabanayagam Tien Yin Wong Ching-Yu Cheng Yih-Chung Tham Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study
description	Abstract We evaluated the 6-year incidence and risk factors of pterygium in a multi-ethnic Asian population. Participants who attended the baseline visit of the Singapore Epidemiology of Eye Diseases Study (year 2004–2011) and returned six years later, were included in this study. Pterygium was diagnosed based on anterior segment photographs. Incident pterygium was defined as presence of pterygium at 6-year follow-up in either eye, among individuals without pterygium at baseline. Multivariable logistic regression models were used to determine factors associated with incident pterygium, adjusting for baseline age, gender, ethnicity, body mass index, occupation type, educational level, income status, smoking, alcohol consumption, presence of hypertension, diabetes and hyperlipidemia. The overall age-adjusted 6-year incidence of pterygium was 1.2% (95% confidence interval [CI] 1.0–1.6%); with Chinese (1.9%; 95% CI 1.4%-2.5%) having the highest incidence rate followed by Malays (1.4%; 95% CI 0.9%-2.1%) and Indians (0.3%; 95% CI 0.3–0.7%). In multivariable analysis, Chinese (compared with Indians; odds ratio [OR] = 4.21; 95% CI 2.12–9.35) and Malays (OR 3.22; 95% CI 1.52–7.45), male (OR 2.13; 95% CI 1.26–3.63), outdoor occupation (OR 2.33; 95% CI 1.16–4.38), and smoking (OR 0.41; 95% CI 0.16–0.87) were significantly associated with incident pterygium. Findings from this multi-ethnic Asian population provide useful information in identifying at-risk individuals for pterygium.
format	article
author	Xiao Ling Fang Crystal Chun Yuen Chong Sahil Thakur Zhi Da Soh Zhen Ling Teo Shivani Majithia Zhi Wei Lim Tyler Hyungtaek Rim Charumathi Sabanayagam Tien Yin Wong Ching-Yu Cheng Yih-Chung Tham
author_facet	Xiao Ling Fang Crystal Chun Yuen Chong Sahil Thakur Zhi Da Soh Zhen Ling Teo Shivani Majithia Zhi Wei Lim Tyler Hyungtaek Rim Charumathi Sabanayagam Tien Yin Wong Ching-Yu Cheng Yih-Chung Tham
author_sort	Xiao Ling Fang
title	Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study
title_short	Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study
title_full	Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study
title_fullStr	Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study
title_full_unstemmed	Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study
title_sort	ethnic differences in the incidence of pterygium in a multi-ethnic asian population: the singapore epidemiology of eye diseases study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c769e01d4b9b46cb9a5a928b96145b71
work_keys_str_mv	AT xiaolingfang ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT crystalchunyuenchong ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT sahilthakur ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT zhidasoh ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT zhenlingteo ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT shivanimajithia ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT zhiweilim ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT tylerhyungtaekrim ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT charumathisabanayagam ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT tienyinwong ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT chingyucheng ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy AT yihchungtham ethnicdifferencesintheincidenceofpterygiuminamultiethnicasianpopulationthesingaporeepidemiologyofeyediseasesstudy
_version_	1718387352586420224

Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study

Ejemplares similares