UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells

Retrotransposons are silenced by an epigenetic mechanism and piRNA pathway in the mammalian germline. Here, the authors report that UHRF1 suppresses retrotransposons by interacting with PRMT5 and PIWI proteins during spermatogenesis.

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Detalles Bibliográficos
Autores principales:	Juan Dong, Xiaoli Wang, Congcong Cao, Yujiao Wen, Akihiko Sakashita, Si Chen, Jin Zhang, Yue Zhang, Liquan Zhou, Mengcheng Luo, Mingxi Liu, Aihua Liao, Satoshi H. Namekawa, Shuiqiao Yuan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c76cb3c76543408a83107042b6b9f1d8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:c76cb3c76543408a83107042b6b9f1d82021-12-02T15:36:01ZUHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells10.1038/s41467-019-12455-42041-1723https://doaj.org/article/c76cb3c76543408a83107042b6b9f1d82019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12455-4https://doaj.org/toc/2041-1723Retrotransposons are silenced by an epigenetic mechanism and piRNA pathway in the mammalian germline. Here, the authors report that UHRF1 suppresses retrotransposons by interacting with PRMT5 and PIWI proteins during spermatogenesis.Juan DongXiaoli WangCongcong CaoYujiao WenAkihiko SakashitaSi ChenJin ZhangYue ZhangLiquan ZhouMengcheng LuoMingxi LiuAihua LiaoSatoshi H. NamekawaShuiqiao YuanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Juan Dong Xiaoli Wang Congcong Cao Yujiao Wen Akihiko Sakashita Si Chen Jin Zhang Yue Zhang Liquan Zhou Mengcheng Luo Mingxi Liu Aihua Liao Satoshi H. Namekawa Shuiqiao Yuan UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
description	Retrotransposons are silenced by an epigenetic mechanism and piRNA pathway in the mammalian germline. Here, the authors report that UHRF1 suppresses retrotransposons by interacting with PRMT5 and PIWI proteins during spermatogenesis.
format	article
author	Juan Dong Xiaoli Wang Congcong Cao Yujiao Wen Akihiko Sakashita Si Chen Jin Zhang Yue Zhang Liquan Zhou Mengcheng Luo Mingxi Liu Aihua Liao Satoshi H. Namekawa Shuiqiao Yuan
author_facet	Juan Dong Xiaoli Wang Congcong Cao Yujiao Wen Akihiko Sakashita Si Chen Jin Zhang Yue Zhang Liquan Zhou Mengcheng Luo Mingxi Liu Aihua Liao Satoshi H. Namekawa Shuiqiao Yuan
author_sort	Juan Dong
title	UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
title_short	UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
title_full	UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
title_fullStr	UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
title_full_unstemmed	UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
title_sort	uhrf1 suppresses retrotransposons and cooperates with prmt5 and piwi proteins in male germ cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c76cb3c76543408a83107042b6b9f1d8
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UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells

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