Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis

Abstract This study aimed to determine whether a surgical lung biopsy is essential for IPF diagnosis with the possible UIP CT pattern. We performed literature searches of the MEDLINE and EMBASE databases and included studies that conducted a radiologic-pathologic evaluation of IPF according to the 2...

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Autores principales:	Heekyung Kim, Soon Ho Yoon, Hyunsook Hong, Seokyung Hahn, Jin Mo Goo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Idiopathic Pulmonary Fibrosis (IPF) UIP Pattern Usual Interstitial Pneumonia (UIP) Surgical Lung Biopsy Inclusive Scenario Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c76ec813733b48e1b2756d3a92ab0fb0
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spelling	oai:doaj.org-article:c76ec813733b48e1b2756d3a92ab0fb02021-12-02T11:40:35ZDiagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis10.1038/s41598-018-34230-z2045-2322https://doaj.org/article/c76ec813733b48e1b2756d3a92ab0fb02018-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-34230-zhttps://doaj.org/toc/2045-2322Abstract This study aimed to determine whether a surgical lung biopsy is essential for IPF diagnosis with the possible UIP CT pattern. We performed literature searches of the MEDLINE and EMBASE databases and included studies that conducted a radiologic-pathologic evaluation of IPF according to the 2011 guideline. Outcomes were pooled using a random-effects model. Twelve studies were included. Pooled proportions of IPF for a UIP pattern were 99% (95%CI, 93% to 100%; I2 = 51.7%) and for a possible UIP pattern were 94% (scenario inclusive of probable IPF; 95%CI, 87% to 99%; I2 = 82.9%) and 88% (scenario exclusive of probable IPF; 95%CI, 79% to 95%; I2 = 82.7%). The pooled percentage difference in the proportion of IPF between the UIP and possible UIP patterns was −2% (95%CI, −4% to 1%; I2 = 0.0%) in the former scenario and 4% (95%CI, 0% to 8%; I2 = 0.1%) in the latter scenario. The proportion of IPF with the possible UIP pattern was moderately correlated with the prevalence of IPF (correlation coefficient, 0.605; 95%CI, 0.550–0.860). There was a negligible pooled percentage difference in the proportion of IPF between the UIP and possible UIP patterns, indicating that IPF diagnosis can be confirmed without biopsy in suspected IPF cases with the possible UIP pattern.Heekyung KimSoon Ho YoonHyunsook HongSeokyung HahnJin Mo GooNature PortfolioarticleIdiopathic Pulmonary Fibrosis (IPF)UIP PatternUsual Interstitial Pneumonia (UIP)Surgical Lung BiopsyInclusive ScenarioMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Idiopathic Pulmonary Fibrosis (IPF) UIP Pattern Usual Interstitial Pneumonia (UIP) Surgical Lung Biopsy Inclusive Scenario Medicine R Science Q
spellingShingle	Idiopathic Pulmonary Fibrosis (IPF) UIP Pattern Usual Interstitial Pneumonia (UIP) Surgical Lung Biopsy Inclusive Scenario Medicine R Science Q Heekyung Kim Soon Ho Yoon Hyunsook Hong Seokyung Hahn Jin Mo Goo Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis
description	Abstract This study aimed to determine whether a surgical lung biopsy is essential for IPF diagnosis with the possible UIP CT pattern. We performed literature searches of the MEDLINE and EMBASE databases and included studies that conducted a radiologic-pathologic evaluation of IPF according to the 2011 guideline. Outcomes were pooled using a random-effects model. Twelve studies were included. Pooled proportions of IPF for a UIP pattern were 99% (95%CI, 93% to 100%; I2 = 51.7%) and for a possible UIP pattern were 94% (scenario inclusive of probable IPF; 95%CI, 87% to 99%; I2 = 82.9%) and 88% (scenario exclusive of probable IPF; 95%CI, 79% to 95%; I2 = 82.7%). The pooled percentage difference in the proportion of IPF between the UIP and possible UIP patterns was −2% (95%CI, −4% to 1%; I2 = 0.0%) in the former scenario and 4% (95%CI, 0% to 8%; I2 = 0.1%) in the latter scenario. The proportion of IPF with the possible UIP pattern was moderately correlated with the prevalence of IPF (correlation coefficient, 0.605; 95%CI, 0.550–0.860). There was a negligible pooled percentage difference in the proportion of IPF between the UIP and possible UIP patterns, indicating that IPF diagnosis can be confirmed without biopsy in suspected IPF cases with the possible UIP pattern.
format	article
author	Heekyung Kim Soon Ho Yoon Hyunsook Hong Seokyung Hahn Jin Mo Goo
author_facet	Heekyung Kim Soon Ho Yoon Hyunsook Hong Seokyung Hahn Jin Mo Goo
author_sort	Heekyung Kim
title	Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis
title_short	Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis
title_full	Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis
title_fullStr	Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis
title_full_unstemmed	Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis
title_sort	diagnosis of idiopathic pulmonary fibrosis in a possible usual interstitial pneumonia pattern: a meta-analysis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c76ec813733b48e1b2756d3a92ab0fb0
work_keys_str_mv	AT heekyungkim diagnosisofidiopathicpulmonaryfibrosisinapossibleusualinterstitialpneumoniapatternametaanalysis AT soonhoyoon diagnosisofidiopathicpulmonaryfibrosisinapossibleusualinterstitialpneumoniapatternametaanalysis AT hyunsookhong diagnosisofidiopathicpulmonaryfibrosisinapossibleusualinterstitialpneumoniapatternametaanalysis AT seokyunghahn diagnosisofidiopathicpulmonaryfibrosisinapossibleusualinterstitialpneumoniapatternametaanalysis AT jinmogoo diagnosisofidiopathicpulmonaryfibrosisinapossibleusualinterstitialpneumoniapatternametaanalysis
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Diagnosis of Idiopathic Pulmonary Fibrosis in a Possible Usual Interstitial Pneumonia Pattern: a meta-analysis

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