Deep learning-based transformation of H&E stained tissues into special stains

Performing multiple histological stains on a biopsy can be costly and time consuming. Here the authors present a method for the digital transformation of H&E stained tissue into special stains (e.g., PAS, Masson’s Trichrome and Jones silver stain), and demonstrate that it improves diagnoses over...

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Autores principales: Kevin de Haan, Yijie Zhang, Jonathan E. Zuckerman, Tairan Liu, Anthony E. Sisk, Miguel F. P. Diaz, Kuang-Yu Jen, Alexander Nobori, Sofia Liou, Sarah Zhang, Rana Riahi, Yair Rivenson, W. Dean Wallace, Aydogan Ozcan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c775e79e449b4ff0bc20220df1cf8595
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spelling oai:doaj.org-article:c775e79e449b4ff0bc20220df1cf85952021-12-02T15:07:56ZDeep learning-based transformation of H&E stained tissues into special stains10.1038/s41467-021-25221-22041-1723https://doaj.org/article/c775e79e449b4ff0bc20220df1cf85952021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25221-2https://doaj.org/toc/2041-1723Performing multiple histological stains on a biopsy can be costly and time consuming. Here the authors present a method for the digital transformation of H&E stained tissue into special stains (e.g., PAS, Masson’s Trichrome and Jones silver stain), and demonstrate that it improves diagnoses over the use of H&E only.Kevin de HaanYijie ZhangJonathan E. ZuckermanTairan LiuAnthony E. SiskMiguel F. P. DiazKuang-Yu JenAlexander NoboriSofia LiouSarah ZhangRana RiahiYair RivensonW. Dean WallaceAydogan OzcanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kevin de Haan
Yijie Zhang
Jonathan E. Zuckerman
Tairan Liu
Anthony E. Sisk
Miguel F. P. Diaz
Kuang-Yu Jen
Alexander Nobori
Sofia Liou
Sarah Zhang
Rana Riahi
Yair Rivenson
W. Dean Wallace
Aydogan Ozcan
Deep learning-based transformation of H&E stained tissues into special stains
description Performing multiple histological stains on a biopsy can be costly and time consuming. Here the authors present a method for the digital transformation of H&E stained tissue into special stains (e.g., PAS, Masson’s Trichrome and Jones silver stain), and demonstrate that it improves diagnoses over the use of H&E only.
format article
author Kevin de Haan
Yijie Zhang
Jonathan E. Zuckerman
Tairan Liu
Anthony E. Sisk
Miguel F. P. Diaz
Kuang-Yu Jen
Alexander Nobori
Sofia Liou
Sarah Zhang
Rana Riahi
Yair Rivenson
W. Dean Wallace
Aydogan Ozcan
author_facet Kevin de Haan
Yijie Zhang
Jonathan E. Zuckerman
Tairan Liu
Anthony E. Sisk
Miguel F. P. Diaz
Kuang-Yu Jen
Alexander Nobori
Sofia Liou
Sarah Zhang
Rana Riahi
Yair Rivenson
W. Dean Wallace
Aydogan Ozcan
author_sort Kevin de Haan
title Deep learning-based transformation of H&E stained tissues into special stains
title_short Deep learning-based transformation of H&E stained tissues into special stains
title_full Deep learning-based transformation of H&E stained tissues into special stains
title_fullStr Deep learning-based transformation of H&E stained tissues into special stains
title_full_unstemmed Deep learning-based transformation of H&E stained tissues into special stains
title_sort deep learning-based transformation of h&e stained tissues into special stains
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c775e79e449b4ff0bc20220df1cf8595
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