Deep learning-based transformation of H&E stained tissues into special stains
Performing multiple histological stains on a biopsy can be costly and time consuming. Here the authors present a method for the digital transformation of H&E stained tissue into special stains (e.g., PAS, Masson’s Trichrome and Jones silver stain), and demonstrate that it improves diagnoses over...
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Nature Portfolio
2021
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oai:doaj.org-article:c775e79e449b4ff0bc20220df1cf85952021-12-02T15:07:56ZDeep learning-based transformation of H&E stained tissues into special stains10.1038/s41467-021-25221-22041-1723https://doaj.org/article/c775e79e449b4ff0bc20220df1cf85952021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25221-2https://doaj.org/toc/2041-1723Performing multiple histological stains on a biopsy can be costly and time consuming. Here the authors present a method for the digital transformation of H&E stained tissue into special stains (e.g., PAS, Masson’s Trichrome and Jones silver stain), and demonstrate that it improves diagnoses over the use of H&E only.Kevin de HaanYijie ZhangJonathan E. ZuckermanTairan LiuAnthony E. SiskMiguel F. P. DiazKuang-Yu JenAlexander NoboriSofia LiouSarah ZhangRana RiahiYair RivensonW. Dean WallaceAydogan OzcanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q |
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Science Q Kevin de Haan Yijie Zhang Jonathan E. Zuckerman Tairan Liu Anthony E. Sisk Miguel F. P. Diaz Kuang-Yu Jen Alexander Nobori Sofia Liou Sarah Zhang Rana Riahi Yair Rivenson W. Dean Wallace Aydogan Ozcan Deep learning-based transformation of H&E stained tissues into special stains |
description |
Performing multiple histological stains on a biopsy can be costly and time consuming. Here the authors present a method for the digital transformation of H&E stained tissue into special stains (e.g., PAS, Masson’s Trichrome and Jones silver stain), and demonstrate that it improves diagnoses over the use of H&E only. |
format |
article |
author |
Kevin de Haan Yijie Zhang Jonathan E. Zuckerman Tairan Liu Anthony E. Sisk Miguel F. P. Diaz Kuang-Yu Jen Alexander Nobori Sofia Liou Sarah Zhang Rana Riahi Yair Rivenson W. Dean Wallace Aydogan Ozcan |
author_facet |
Kevin de Haan Yijie Zhang Jonathan E. Zuckerman Tairan Liu Anthony E. Sisk Miguel F. P. Diaz Kuang-Yu Jen Alexander Nobori Sofia Liou Sarah Zhang Rana Riahi Yair Rivenson W. Dean Wallace Aydogan Ozcan |
author_sort |
Kevin de Haan |
title |
Deep learning-based transformation of H&E stained tissues into special stains |
title_short |
Deep learning-based transformation of H&E stained tissues into special stains |
title_full |
Deep learning-based transformation of H&E stained tissues into special stains |
title_fullStr |
Deep learning-based transformation of H&E stained tissues into special stains |
title_full_unstemmed |
Deep learning-based transformation of H&E stained tissues into special stains |
title_sort |
deep learning-based transformation of h&e stained tissues into special stains |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/c775e79e449b4ff0bc20220df1cf8595 |
work_keys_str_mv |
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