SARS-CoV-2 binding and neutralizing antibody levels after Ad26.COV2.S vaccination predict durable protection in rhesus macaques

SARS-CoV-2 binding and neutralizing antibody levels after Ad26.COV2.S vaccination predict durable protection in rhesus macaques

Several COVID-19 vaccines have received emergency approval, but durability of protection is unclear. Here, the authors describe correlates of protection (CoP) for the Ad26.COV2.S vaccine in rhesus macaques and report that CoP predict the protection observed 6 months post vaccination.

Guardado en:
Detalles Bibliográficos
Autores principales: Ramon Roozendaal, Laura Solforosi, Daniel J. Stieh, Jan Serroyen, Roel Straetemans, Anna Dari, Muriel Boulton, Frank Wegmann, Sietske K. Rosendahl Huber, Joan E. M. van der Lubbe, Jenny Hendriks, Mathieu Le Gars, Liesbeth Dekking, Dominika N. Czapska-Casey, Nuria Guimera, Sarah Janssen, Sarah Tete, Abishek Chandrashekar, Noe B. Mercado, Jingyou Yu, Wouter Koudstaal, Juan J. Perez-Ruixo, Jerry Sadoff, Dan H. Barouch, Hanneke Schuitemaker, Roland Zahn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/c77c130d228d404b88e0e8b1e5e20f78
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Several COVID-19 vaccines have received emergency approval, but durability of protection is unclear. Here, the authors describe correlates of protection (CoP) for the Ad26.COV2.S vaccine in rhesus macaques and report that CoP predict the protection observed 6 months post vaccination.

Ejemplares similares