Seroprevalence of Chikungunya (CHIK) Infection during Non Epidemic Periods in Chennai, Southern India
Introduction: Chikungunya (CHIK) infection has caused many outbreaks in India with more than 13 lac people affected by the disease. Epidemics of CHIK infection occur during post monsoon period when there is a high vector density. Evidences on the prevalence of CHIK infection during non epidemic...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
JCDR Research and Publications Private Limited
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/c77f46251d274f2eb1918c5fca9f6051 |
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| Sumario: | Introduction: Chikungunya (CHIK) infection has caused many
outbreaks in India with more than 13 lac people affected by
the disease. Epidemics of CHIK infection occur during post
monsoon period when there is a high vector density. Evidences
on the prevalence of CHIK infection during non epidemic periods
are limited.
Aim: To determine the seroprevalence of CHIK infection during
non epidemic periods among patients attending fever clinic in
Chennai, Southern India.
Materials and Methods: This cross-sectional study was done in
180 suspected cases of CHIK infection between the months of
September 2014 and February 2015. A 5 mL of blood samples were
collected from the suspected cases and serum was separated to
detect for the presence of CHIK-IgM antibody by using CHIK-IgM
antibody capture Enzyme Linked Immunosorbent Assay (ELISA)
kit. Chi-square test was done to find out the statistical significance
with p-value <0.05 kept as statistically significant.
Results: The seroprevalence of CHIK infection during non epidemic
periods was found to be 5.5% (10/180). Fever and joint pain
were the major complaints present in all the study population.
All the seronegative cases were tested for the presence of other
infections and it was found that 13% were positive for typhoid,
9% were positive for leptospirosis, 4% for malaria and 2% for
dengue infections.
Conclusion: There are no vaccines or specific medications available
till date. Prevention is the only effective approach against the
disease. Even though the prevalence of CHIK infection is low
during non epidemic periods, strict vector control and elimination
of mosquito breeding sites are very important in controlling the
disease transmission. |
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