Single nucleus multi-omics regulatory landscape of the murine pituitary

The pituitary gland plays important roles in the regulation of key physiological functions. Here the authors provide a multiomics atlas including transcriptome, chromatin accessibility, and methylation status of over 70,000 single nuclei (sn) from mouse pituitaries.

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Autores principales: Frederique Ruf-Zamojski, Zidong Zhang, Michel Zamojski, Gregory R. Smith, Natalia Mendelev, Hanqing Liu, German Nudelman, Mika Moriwaki, Hanna Pincas, Rosa Gomez Castanon, Venugopalan D. Nair, Nitish Seenarine, Mary Anne S. Amper, Xiang Zhou, Luisina Ongaro, Chirine Toufaily, Gauthier Schang, Joseph R. Nery, Anna Bartlett, Andrew Aldridge, Nimisha Jain, Gwen V. Childs, Olga G. Troyanskaya, Joseph R. Ecker, Judith L. Turgeon, Corrine K. Welt, Daniel J. Bernard, Stuart C. Sealfon
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c782850ef40d4c03ac0d69ac797d06d6
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spelling oai:doaj.org-article:c782850ef40d4c03ac0d69ac797d06d62021-12-02T17:01:35ZSingle nucleus multi-omics regulatory landscape of the murine pituitary10.1038/s41467-021-22859-w2041-1723https://doaj.org/article/c782850ef40d4c03ac0d69ac797d06d62021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22859-whttps://doaj.org/toc/2041-1723The pituitary gland plays important roles in the regulation of key physiological functions. Here the authors provide a multiomics atlas including transcriptome, chromatin accessibility, and methylation status of over 70,000 single nuclei (sn) from mouse pituitaries.Frederique Ruf-ZamojskiZidong ZhangMichel ZamojskiGregory R. SmithNatalia MendelevHanqing LiuGerman NudelmanMika MoriwakiHanna PincasRosa Gomez CastanonVenugopalan D. NairNitish SeenarineMary Anne S. AmperXiang ZhouLuisina OngaroChirine ToufailyGauthier SchangJoseph R. NeryAnna BartlettAndrew AldridgeNimisha JainGwen V. ChildsOlga G. TroyanskayaJoseph R. EckerJudith L. TurgeonCorrine K. WeltDaniel J. BernardStuart C. SealfonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Frederique Ruf-Zamojski
Zidong Zhang
Michel Zamojski
Gregory R. Smith
Natalia Mendelev
Hanqing Liu
German Nudelman
Mika Moriwaki
Hanna Pincas
Rosa Gomez Castanon
Venugopalan D. Nair
Nitish Seenarine
Mary Anne S. Amper
Xiang Zhou
Luisina Ongaro
Chirine Toufaily
Gauthier Schang
Joseph R. Nery
Anna Bartlett
Andrew Aldridge
Nimisha Jain
Gwen V. Childs
Olga G. Troyanskaya
Joseph R. Ecker
Judith L. Turgeon
Corrine K. Welt
Daniel J. Bernard
Stuart C. Sealfon
Single nucleus multi-omics regulatory landscape of the murine pituitary
description The pituitary gland plays important roles in the regulation of key physiological functions. Here the authors provide a multiomics atlas including transcriptome, chromatin accessibility, and methylation status of over 70,000 single nuclei (sn) from mouse pituitaries.
format article
author Frederique Ruf-Zamojski
Zidong Zhang
Michel Zamojski
Gregory R. Smith
Natalia Mendelev
Hanqing Liu
German Nudelman
Mika Moriwaki
Hanna Pincas
Rosa Gomez Castanon
Venugopalan D. Nair
Nitish Seenarine
Mary Anne S. Amper
Xiang Zhou
Luisina Ongaro
Chirine Toufaily
Gauthier Schang
Joseph R. Nery
Anna Bartlett
Andrew Aldridge
Nimisha Jain
Gwen V. Childs
Olga G. Troyanskaya
Joseph R. Ecker
Judith L. Turgeon
Corrine K. Welt
Daniel J. Bernard
Stuart C. Sealfon
author_facet Frederique Ruf-Zamojski
Zidong Zhang
Michel Zamojski
Gregory R. Smith
Natalia Mendelev
Hanqing Liu
German Nudelman
Mika Moriwaki
Hanna Pincas
Rosa Gomez Castanon
Venugopalan D. Nair
Nitish Seenarine
Mary Anne S. Amper
Xiang Zhou
Luisina Ongaro
Chirine Toufaily
Gauthier Schang
Joseph R. Nery
Anna Bartlett
Andrew Aldridge
Nimisha Jain
Gwen V. Childs
Olga G. Troyanskaya
Joseph R. Ecker
Judith L. Turgeon
Corrine K. Welt
Daniel J. Bernard
Stuart C. Sealfon
author_sort Frederique Ruf-Zamojski
title Single nucleus multi-omics regulatory landscape of the murine pituitary
title_short Single nucleus multi-omics regulatory landscape of the murine pituitary
title_full Single nucleus multi-omics regulatory landscape of the murine pituitary
title_fullStr Single nucleus multi-omics regulatory landscape of the murine pituitary
title_full_unstemmed Single nucleus multi-omics regulatory landscape of the murine pituitary
title_sort single nucleus multi-omics regulatory landscape of the murine pituitary
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c782850ef40d4c03ac0d69ac797d06d6
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