A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus

ABSTRACT While glutamine is a nonessential amino acid that can be synthesized from glucose, some cancer cells primarily depend on glutamine for their growth, proliferation, and survival. Numerous types of cancer also depend on asparagine for cell proliferation. The underlying mechanisms of the gluta...

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Autores principales: Ying Zhu, Tingting Li, Suzane Ramos da Silva, Jae-Jin Lee, Chun Lu, Hyungjin Eoh, Jae U. Jung, Shou-Jiang Gao
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/c78544eb784a43aba0a2d29677c103e6
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