Prestimulation of CD2 confers resistance to HIV-1 latent infection in blood resting CD4 T cells
Summary: HIV-1 infects blood CD4 T cells through the use of CD4 and CXCR4 or CCR5 receptors, which can be targeted through blocking viral binding to CD4/CXCR4/CCR5 or virus-cell fusion. Here we describe a novel mechanism by which HIV-1 nuclear entry can also be blocked through targeting a non-entry...
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Main Authors: | Sijia He, Jia Guo, Yajing Fu, Mark Spear, Chaolong Qin, Shuai Fu, Zongqiang Cui, Wenwen Jin, Xuehua Xu, Wanjun Chen, Hong Shang, Yuntao Wu |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Subjects: | |
Online Access: | https://doaj.org/article/c78825a51f2d4c4ca0d788a5bcae008a |
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