Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia

Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia

Working memory requires the brain to switch between cognitive states and activity patterns. Here, the authors show that the steering of these neural network dynamics is influenced by dopamine D1- and D2-receptor function and altered in schizophrenia.

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Auteurs principaux: Urs Braun, Anais Harneit, Giulio Pergola, Tommaso Menara, Axel Schäfer, Richard F. Betzel, Zhenxiang Zang, Janina I. Schweiger, Xiaolong Zhang, Kristina Schwarz, Junfang Chen, Giuseppe Blasi, Alessandro Bertolino, Daniel Durstewitz, Fabio Pasqualetti, Emanuel Schwarz, Andreas Meyer-Lindenberg, Danielle S. Bassett, Heike Tost
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Science
Q
Accès en ligne:https://doaj.org/article/c7893d2c5a3340b7ab44d7d212a42fbc
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Résumé:Working memory requires the brain to switch between cognitive states and activity patterns. Here, the authors show that the steering of these neural network dynamics is influenced by dopamine D1- and D2-receptor function and altered in schizophrenia.

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