Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia

Working memory requires the brain to switch between cognitive states and activity patterns. Here, the authors show that the steering of these neural network dynamics is influenced by dopamine D1- and D2-receptor function and altered in schizophrenia.

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Autores principales:	Urs Braun, Anais Harneit, Giulio Pergola, Tommaso Menara, Axel Schäfer, Richard F. Betzel, Zhenxiang Zang, Janina I. Schweiger, Xiaolong Zhang, Kristina Schwarz, Junfang Chen, Giuseppe Blasi, Alessandro Bertolino, Daniel Durstewitz, Fabio Pasqualetti, Emanuel Schwarz, Andreas Meyer-Lindenberg, Danielle S. Bassett, Heike Tost
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c7893d2c5a3340b7ab44d7d212a42fbc
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spelling	oai:doaj.org-article:c7893d2c5a3340b7ab44d7d212a42fbc2021-12-02T17:52:24ZBrain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia10.1038/s41467-021-23694-92041-1723https://doaj.org/article/c7893d2c5a3340b7ab44d7d212a42fbc2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23694-9https://doaj.org/toc/2041-1723Working memory requires the brain to switch between cognitive states and activity patterns. Here, the authors show that the steering of these neural network dynamics is influenced by dopamine D1- and D2-receptor function and altered in schizophrenia.Urs BraunAnais HarneitGiulio PergolaTommaso MenaraAxel SchäferRichard F. BetzelZhenxiang ZangJanina I. SchweigerXiaolong ZhangKristina SchwarzJunfang ChenGiuseppe BlasiAlessandro BertolinoDaniel DurstewitzFabio PasqualettiEmanuel SchwarzAndreas Meyer-LindenbergDanielle S. BassettHeike TostNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Urs Braun Anais Harneit Giulio Pergola Tommaso Menara Axel Schäfer Richard F. Betzel Zhenxiang Zang Janina I. Schweiger Xiaolong Zhang Kristina Schwarz Junfang Chen Giuseppe Blasi Alessandro Bertolino Daniel Durstewitz Fabio Pasqualetti Emanuel Schwarz Andreas Meyer-Lindenberg Danielle S. Bassett Heike Tost Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
description	Working memory requires the brain to switch between cognitive states and activity patterns. Here, the authors show that the steering of these neural network dynamics is influenced by dopamine D1- and D2-receptor function and altered in schizophrenia.
format	article
author	Urs Braun Anais Harneit Giulio Pergola Tommaso Menara Axel Schäfer Richard F. Betzel Zhenxiang Zang Janina I. Schweiger Xiaolong Zhang Kristina Schwarz Junfang Chen Giuseppe Blasi Alessandro Bertolino Daniel Durstewitz Fabio Pasqualetti Emanuel Schwarz Andreas Meyer-Lindenberg Danielle S. Bassett Heike Tost
author_facet	Urs Braun Anais Harneit Giulio Pergola Tommaso Menara Axel Schäfer Richard F. Betzel Zhenxiang Zang Janina I. Schweiger Xiaolong Zhang Kristina Schwarz Junfang Chen Giuseppe Blasi Alessandro Bertolino Daniel Durstewitz Fabio Pasqualetti Emanuel Schwarz Andreas Meyer-Lindenberg Danielle S. Bassett Heike Tost
author_sort	Urs Braun
title	Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
title_short	Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
title_full	Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
title_fullStr	Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
title_full_unstemmed	Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
title_sort	brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c7893d2c5a3340b7ab44d7d212a42fbc
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Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia

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